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Peer-ReviewedPubMedResearch ArticleDiagnosticClinical nuclear medicine · 2026

A Case of FDG-Avid but FAPI-Negative Peritoneal Metastatic Gastrointestinal Stromal Tumor.

Zhou L, Zhang S, Liu W, Lei Q, Qiu L.

Abstract

An 80-year-old man underwent 18F-FDG PET/CT and 68Ga-FAPI PET/CT for a biopsy-confirmed metastatic gastrointestinal stromal tumor (GIST). While 18F-FDG PET/CT revealed intensely increased uptake in the perisplenic, right abdominal, and pelvic peritoneal implants, 68Ga-FAPI PET/CT unexpectedly showed negligible tracer uptake across all corresponding lesions.

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