Authorised Indian Distributor
Saxsons Group
New Delhi, India · Since 1997
Dual Gamma + Fluorescence Sentinel Node ProbeEuroprobe™ Gamma + Fluorescence — Dual Opto-Nuclear Detection · CdTe Gamma + ICG NIR in One Probe
Dual-modality intraoperative sentinel lymph node biopsy probe — one hand-held or laparoscopic probe carries both a CdTe gamma channel (Tc-99m, I-125, In-111) and an indocyanine-green (ICG) near-infrared fluorescence channel. Published dual-modality SLN detection rates approach 100 % vs ~95 % for either channel alone, across breast cancer, cutaneous melanoma, cervical + endometrial SLN and prostate / bladder SLN protocols — because the gamma probe finds the node at depth and the ICG fluorescence channel confirms it at the dissection plane. Two probe geometries cover open (SOE 3214) and 12 mm-trocar laparoscopic (SOE 3214-AF) workflows. Foot-switch modality control keeps the surgeon scrubbed; fluorescence detection works under normal OR lighting — no room blackout. Fluorescence module clips onto the same Europrobe 3.2 console, so a hospital already running a gamma-only Europrobe upgrades to dual modality without replacing the platform. Distributed, installed, trained and serviced across India by Saxsons Healthcare.
Key Features
- World-first single dual-channel probe — CdTe gamma and ICG NIR fluorescence detection from the same probe body
- Foot-switch modality control — surgeon stays scrubbed and switches gamma ↔ fluorescence at the dissection cadence
- Fluorescence detection threshold < 1 nmol ICG — comfortably below standard pre-injection working concentration
- Operates under normal OR lighting — no room blackout required; ambient overhead light does not saturate the NIR channel
- Same console as the Europrobe 3.2 gamma platform — add-on fluorescence module clips into the existing hospital deployment
All Features
- World-first single dual-channel probe — CdTe gamma and ICG NIR fluorescence detection from the same probe body
- Foot-switch modality control — surgeon stays scrubbed and switches gamma ↔ fluorescence at the dissection cadence
- Fluorescence detection threshold < 1 nmol ICG — comfortably below standard pre-injection working concentration
- Operates under normal OR lighting — no room blackout required; ambient overhead light does not saturate the NIR channel
- Same console as the Europrobe 3.2 gamma platform — add-on fluorescence module clips into the existing hospital deployment
- CdTe gamma channel covers 20–300 keV (optimum 20–170 keV) — ⁹⁹ᵐTc, ¹²⁵I, ¹¹¹In isotope library
- Open opto-nuclear probe — SOE 3214 (12 mm Ø, 194 mm length) for breast, melanoma, ENT and open gynae cases
- Frontal laparoscopic opto-nuclear probe — SOE 3214-AF (12.2 mm Ø, 426 mm length) trans-trocar for robotic / laparoscopic gynae + urological cases
- Medical-grade stainless-steel probe body — autoclavable handle interface; OR-cleaning compatible
- Sterile single-use biocompatible probe cover — ISO 10993-5 / -10 / -11 compliance
- No specific installation requirements beyond standard OR power; compact 1 kg add-on module
- EU MDR Class IIa (39483-0) and FDA-registered (9032627) — regulatory-ready for hospital procurement
Technical Specifications
| Detection modalities | CdTe (gamma) + NIR fluorescence (ICG) |
| Fluorescence sensitivity | < 1 nmol ICG |
| Gamma energy range | 20–300 keV (optimum 20–170 keV) |
| Compatible isotopes | ⁹⁹ᵐTc · ¹²⁵I · ¹¹¹In |
| Modality control | Foot-switch — sterile, no console interaction |
| Operating light | Normal OR lighting; no blackout required |
| Probe library | SOE 3214 (open opto-nuclear, 12 mm Ø, 194 mm) · SOE 3214-AF (frontal laparoscopic, 12.2 mm Ø, 426 mm) |
| Probe material | Medical-grade stainless steel; ISO 10993-5 / -10 / -11 biocompatible |
| Sterility | Sterile single-use probe cover |
| Module dimensions | 55 mm (H) × 233 mm (W) × 270 mm (D); 1 kg |
| Console compatibility | Europrobe 3.2 console — fluorescence is an add-on module to the gamma platform |
| Power | Standard OR power; no specific installation requirements |
| Regulatory | EU MDR Class IIa (39483-0); FDA registered 9032627 |
Applications
Where dual gamma + ICG fluorescence beats either modality alone
Breast SLN — dual gamma + ICG
Tc-99m-nanocolloid + ICG-99m hybrid tracer or sequential ICG injection. The dual probe finds the node by gamma signal at depth and by ICG fluorescence at the dissection plane. Published series report dual-modality detection rates approaching 100 % vs ~95 % for either modality alone.
Melanoma SLN — dual gamma + ICG
Intradermal Tc-99m-nanocolloid + sub-dermal ICG at the primary site. Dual modality reduces the false-negative rate at multiple-basin and intransit drainage where gamma-only mapping can miss a faint node.
Gynaecological SLN — laparoscopic
Para-cervical Tc-99m + ICG injection in cervical and endometrial cancer. The SOE 3214-AF frontal laparoscopic probe carries both channels through the standard 12 mm trocar — the surgeon does not swap to a separate fluorescence-only laparoscope.
ENT SLN (oral cavity)
Peri-tumour Tc-99m-nanocolloid + ICG injection in oral SCC; the dual channel discriminates ipsilateral level I-III nodes against a busy floor-of-mouth gamma background.
Why Dual Gamma + Fluorescence Sentinel Node Probe?
Threshold for detectable ICG fluorescence — comfortably below the working ICG concentration after standard pre-operative subcutaneous injection. The probe finds the node before the surgical-grade NIR camera does in the deep tissue plane.
Selection of detection modality through a foot-switch — no scrubbed-hand interaction with the console. Sterile workflow stays intact; the surgeon switches gamma ↔ fluorescence at the dissection cadence.
Fluorescence detection works under normal OR lighting — no room blackout required. The NIR wavelength is outside the visible spectrum; ambient overhead light does not saturate the channel.
Where dual modality is used
Anatomical map — SOE 3214 vs SOE 3214-AF per surgical area
Eight surgical areas where the dual gamma + ICG fluorescence workflow has published evidence. Open SOE 3214 covers the breast / melanoma / head & neck / vulvar / inguinal / penile SLN; laparoscopic SOE 3214-AF covers pelvic and prostate / bladder SLN trans-trocar. Hover any marker for the probe image.
1 · Head & neck SLN
Oral SCC · ICG + Tc-99m peri-tumoural
Open · SOE 3214
2 · Axillary SLN — breast
Hybrid ICG-99mTc-nanocolloid · peri-areolar
Open · SOE 3214
3 · Melanoma SLN — skin
Multi-basin drainage · sub-dermal ICG + Tc-99m
Open · SOE 3214
4 · Inguinal SLN
Melanoma · penile · vulvar drainage
Open · SOE 3214
Head & neck SLN
Oral SCC · ICG + Tc-99m peri-tumoural
Open · SOE 3214
Axillary SLN — breast
Hybrid ICG-99mTc-nanocolloid peri-areolar
Open · SOE 3214
Melanoma SLN — skin
Sub-dermal ICG + Tc-99m at primary site
Open · SOE 3214
Pelvic SLN — cervix / endometrium
Laparoscopic / robotic · Tc-99m + ICG paracervical
Laparoscopic · SOE 3214-AF (trans-trocar)
Prostate / bladder SLN
Robotic / laparoscopic urology · Tc-99m + ICG
Laparoscopic · SOE 3214-AF (trans-trocar)
Vulvar SLN
Early vulvar cancer · Tc-99m + ICG peri-tumour
Open · SOE 3214
Penile SLN
Penile cancer · intradermal Tc-99m + ICG
Open · SOE 3214
Inguinal SLN
Melanoma · penile · vulvar drainage
Open · SOE 3214
5 · Pelvic SLN — cervix / endometrium
Laparoscopic / robotic · paracervical injection
Laparoscopic · SOE 3214-AF
6 · Vulvar SLN
Early vulvar cancer · Tc-99m + ICG peri-tumour
Open · SOE 3214
7 · Penile SLN
Penile cancer · intradermal Tc-99m + ICG
Open · SOE 3214
8 · Prostate / bladder SLN
Robotic / laparoscopic urology · Tc-99m + ICG
Laparoscopic · SOE 3214-AF
Both probes carry both channels
CdTe gamma (20–300 keV) + NIR ICG fluorescence (< 1 nmol) — foot-switch toggled · normal OR light
Add-on to Europrobe 3.2 console
Same console as the gamma-only platform; fluorescence module is the upgrade path
Probe geometries
Pick the geometry, pick the surgical approach
Two dual-channel probe geometries cover the open and laparoscopic OR workflow. Both carry the CdTe gamma channel AND the NIR ICG fluorescence channel in the same probe body.
| Model | Geometry | Size | Use |
|---|---|---|---|
| SOE 3214 | Standard opto-nuclear | 12 mm Ø · 194 mm length | Open SLN — breast, melanoma, head & neck. Single probe carries both CdTe gamma and NIR fluorescence channels. |
| SOE 3214-AF | Frontal laparoscopic opto-nuclear | 12.2 mm Ø · 426 mm length | Trans-trocar SLN for gynaecological + urological robotic / laparoscopic cases. Frontal-tip both-channel detection. |
What the dual platform brings
Six things the dual opto-nuclear probe delivers
| Capability | Why it matters in theatre |
|---|---|
| Single dual-channel probe per case | One probe, one cable, one sterile cover — both gamma + ICG fluorescence detection from the same body. No probe-swap mid-case; sterile field stays intact. |
| Foot-switch modality control | Surgeon stays scrubbed; the foot-switch toggles gamma ↔ fluorescence without breaking the dissection cadence. |
| Works under normal OR lighting | NIR fluorescence channel is outside the visible spectrum; no room blackout required. OR list stays on schedule; nursing-circulator stress goes down. |
| Same console as Europrobe 3.2 gamma platform | The fluorescence module is an add-on to the Europrobe 3.2 console. A hospital that already runs a gamma-only Europrobe upgrades to dual-modality without replacing the platform. |
| Standard CdTe energy range | 20–300 keV gamma window (optimum 20–170 keV) covers ⁹⁹ᵐTc, ¹²⁵I, ¹¹¹In — the same workhorse range as the gamma-only platform. |
| Sterile single-use probe cover | Biocompatible cover ISO 10993 compliance; standard sterile field maintained across the dual-channel probe geometry. |
Catalogs & Resources
Product brochure, AERB radioisotope-handling framework and CDSCO ICG reference
Europrobe Gamma / Fluorescence product brochure
Dual opto-nuclear probe specifications, ICG sensitivity, probe geometries and accessory matrix.
AERB Safety Code for Nuclear Medicine Facility
Indian regulatory framework — pre-operative ⁹⁹ᵐTc injection authorisation, theatre handling and specimen-disposal expectations.
CDSCO — Indocyanine green dye (drug regulatory reference)
Central Drugs Standard Control Organisation reference for ICG as the operative fluorescence agent.
Videos
Europrobe™ Gamma + Fluorescence
More for this product
Each card opens a focused post for a specific specialty — peer-reviewed evidence and clinical workflow, written for the persona you select.
FAQ
Gamma + ICG fluorescence sentinel lymph node biopsy — questions we hear from Indian surgical-oncology teams
What a dual gamma + fluorescence probe does in the operating theatre, why ICG adds value on top of gamma-only SLN mapping, which laparoscopic and open workflows it supports, and how the dual-modality probe is delivered in India.
Q.What is a dual gamma + fluorescence sentinel-node probe?
A dual gamma + ICG-fluorescence probe (also called an opto-nuclear probe) combines two intraoperative detection channels in a single hand-held or laparoscopic probe: a CdTe gamma channel that finds the radioactive (Tc-99m) sentinel lymph node signal at depth, and a near-infrared (NIR) fluorescence channel that reads the indocyanine green (ICG) signal at the dissection plane. Both channels look at the same node from the same probe body, so the surgeon does not swap between a gamma probe and a separate ICG camera during the case.
Q.Why use ICG fluorescence in addition to gamma-probe SLN?
Gamma-probe-only sentinel-node biopsy has an inherent limit — the shine-through from the injection site can mask a nearby faint node, and multi-basin melanoma drainage sometimes hides a second-echelon node with lower isotope uptake. Adding an ICG fluorescence channel gives a second, independent visual signal at the dissection plane. Published dual-modality series report SLN detection rates approaching 100 %, versus ~95 % for either modality alone, in breast, melanoma and gynae-onco protocols.
Q.Which ICG-99m hybrid tracer protocols does the Europrobe Gamma + Fluorescence support?
The system supports both the ICG-99m hybrid tracer (a single injectate combining Tc-99m nanocolloid and ICG, described in Van den Berg / KleinJan 2015-2018) and sequential Tc-99m + ICG injection protocols. Both approaches feed the same dual probe workflow.
Q.Can the fluorescence probe be used laparoscopically?
Yes — the SOE 3214-AF frontal laparoscopic probe (12.2 mm Ø × 426 mm) passes through standard 12 mm trocars and carries both the CdTe gamma channel and the ICG fluorescence channel. Gynae-onco pelvic SLN (cervix, endometrium) and urology pelvic SLN (prostate, bladder) workflows run without swapping to a separate laparoscopic fluorescence camera.
Q.Does fluorescence detection require the OR to be dark?
No. The fluorescence channel reads near-infrared (NIR) light — outside the visible spectrum — so ambient overhead OR lighting does not saturate it. Normal theatre lighting stays on. That matters for OR list-flow and for anaesthetic-monitoring visibility.
Q.Is the Europrobe Gamma + Fluorescence dual probe available in India?
Yes — supplied, installed, trained and serviced across India by Saxsons Healthcare. The fluorescence module clips into the existing Europrobe 3.2 console; hospitals already running a gamma-only Europrobe can upgrade to dual-modality without replacing the platform.
Dual Gamma + Fluorescence Sentinel Node Probe supplier in India — Saxsons Group
Saxsons Group has supplied onco surgery equipment to over 1,000 Indian hospitals since 1988. Every consignment of Dual Gamma + Fluorescence Sentinel Node Probe ships with cold-chain logistics, AERB import documentation, CDSCO registration references and a Certificate of Analysis delivered before dispatch — the paperwork your radiation-safety and procurement teams need, pre-assembled.
- Nationwide delivery footprint — every metro and tier-2 city in India, scheduled to your treatment / procedure calendar.
- AERB & CDSCO documentation — import licence, radiation-safety paperwork and RSO briefing pre-assembled for the audit file.
- 40+ years in Indian oncology — long-standing supply relationships with AIIMS, Tata Memorial, and hundreds of tertiary-care centres.
- Single point of accountability — one purchase order, one delivery contact, one after-sales team across the whole product family.
Also supplied by Saxsons Group across India
The single probe that carries both modalities
Contact Saxsons Healthcare for probe-geometry selection per OR list (open vs laparoscopic), sterile-cover quantities, installation as an add-on to an existing Europrobe 3.2 console, training, AMC and warranty — distributed and supported across India.