Authorised Indian Distributor
Saxsons Group
New Delhi, India · Since 1997
CRP™ Radiopharmaceutical Dispensing SystemAutomated Vial-Dispensing Module
The automation that turns a shielded hot cell into a fully automated radiopharmacy dispensing bench. Drops into any laminar-flow cell with a calibrator well, dispenses open and closed vials under sterile conditions, hits <1% volume deviation, and runs without the operator reaching in.
Key Features
- Automated dispensing of open and closed vials under sterile conditions ((the manufacturer spec))
- Volume / weight deviation from target guaranteed to be less than 1% ((the manufacturer spec))
- EU GMP Annex 1 compliant — designed for aseptic radiopharmaceutical dispensing
- Two variants — CRP Compact (open vials, optional piercing module for closed vials) and CRP Compact plus (open vials with crimping or push-fit capping)
- Drops into any shielded laminar-flow hot cell with a calibrator well and telemanipulator ((the manufacturer spec))
All Features
- Automated dispensing of open and closed vials under sterile conditions ((the manufacturer spec))
- Volume / weight deviation from target guaranteed to be less than 1% ((the manufacturer spec))
- EU GMP Annex 1 compliant — designed for aseptic radiopharmaceutical dispensing
- Two variants — CRP Compact (open vials, optional piercing module for closed vials) and CRP Compact plus (open vials with crimping or push-fit capping)
- Drops into any shielded laminar-flow hot cell with a calibrator well and telemanipulator ((the manufacturer spec))
- Compatible with crimped aluminum-ring caps and push-fit caps
- Handles the whole radiopharmaceutical dispensing process automatically — operator interacts via the control PC, not through the cell
- In India, primary use is F-18 PET tracer unit-dose dispensing (FDG, NaF, F-DOPA, PSMA-1007) — Saxsons-supplied market reality
- 100 CRP units installed around the world (the manufacturer figure)
- Integrates with the FLEX dispensing hot cell as the inside-cell automation layer
- Available through Saxsons Group with full AERB import documentation for the Indian market
Technical Specifications
| Type | Automated radiopharmaceutical dispensing module — drops into a shielded laminar-flow hot cell |
| Variants | CRP Compact; CRP Compact plus |
| Volume / weight precision | < 1 % deviation from target ((the manufacturer spec)) |
| Vial types — Compact | Open vials with rubber-stopper + crimped aluminum-ring capping; optional piercing module for closed vials |
| Vial types — Compact plus | Open vials with rubber-stopper + crimped aluminum-ring capping or push-fit capping |
| Closed-vial dispensing | Yes — via septum piercing (optional on Compact, standard on integrated FLEX µ DDS-A workflows) |
| Host cell requirements | Shielded laminar-flow cell with calibrator well and telemanipulator |
| Shielding | Provided by the host hot cell — CRP itself is the inside-cell module, not the shielded enclosure |
| Standards alignment | EU GMP Annex 1 compliant (the manufacturer marketing language) |
| Primary isotope use (India) | F-18 PET tracers (FDG, NaF, F-DOPA, PSMA-1007) — Saxsons-supplied market focus |
| Install base | 100 CRP units installed worldwide (the manufacturer figure) |
| Indian regulatory path | AERB Regulatory Requirements & Guidelines for Medical Cyclotron Facility (2017) — applies to the host cell |
Applications
F-18 unit-dose automation inside any shielded laminar-flow cell
F-18 PET tracer unit-dose dispensing
In India, the primary daily workload — FDG, NaF, F-DOPA and PSMA-1007 unit doses drawn from cyclotron-produced bulk into patient syringes / vials. CRP runs the automation; the FLEX (or similar) provides the Grade A shielded environment around it.
Closed-vial dispensing
CRP Compact + piercing option (or CRP Compact plus in its standard config) handles closed-vial dispensing via septum piercing — keeping the dispensed product container sealed from atmospheric exposure.
Open-vial dispensing with crimping
CRP Compact and Compact plus both handle open-vial dispensing with subsequent rubber-stopper + crimped aluminum-ring capping in a single automated sequence.
Push-fit capping (Compact plus)
CRP Compact plus adds push-fit cap support — useful for vial workflows where crimping is not the preferred final-seal method.
Inside-cell automation upgrade
An existing manual hot cell with a calibrator well and telemanipulator can be upgraded to fully automated dispensing by installing a CRP — no full cell replacement needed ((the manufacturer )"compact dimensions, any type of shielded LAF cell" spec).
FLEX + CRP integrated workflow
Specified together, the FLEX dispensing hot cell hosts the CRP as its inside-cell automation. One Saxsons-supplied package: the shielded Grade A environment + the automated dispensing module + the AERB import path.
Why CRP?
Patient dose accuracy starts with dispense accuracy. (the manufacturer )guarantees CRP volume / weight deviation under 1% — the precision floor a modern radiopharmacy expects from automated unit-dose dispensing.
100 CRP units in service around the world per Tema's figure — a meaningfully large reference base for a niche piece of radiopharmacy automation, not a first-of-its-kind risk for the Indian buyer.
CRP installs into any shielded laminar-flow cell with a calibrator well and a telemanipulator. The existing investment in a hot cell carries forward — CRP adds the automation layer on top.
Catalogs & Resources
Manufacturer product page, brochure PDF and the two the manufacturer Vimeo product demos. The host hot cell (FLEX) standards library is on its own knowledge hub.
CRP — Manufacturer product page
Manufacturer page with the CRP Compact and CRP Compact plus specification, vial-type matrix and the brochure download form.
CRP Compact — Manufacturer brochure (PDF)
CRP Compact / CRP Compact plus product brochure (2024 edition).
CRP Compact — the manufacturer demo (Vimeo)
Manufacturer product demo of the CRP Compact dispensing module.
CRP Compact plus — the manufacturer demo (Vimeo)
Manufacturer product demo of the CRP Compact plus dispensing module with push-fit cap support.
CRP™ Dispensing System
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Each card opens a focused post for a specific specialty — peer-reviewed evidence and clinical workflow, written for the persona you select.
FAQ
Automated radiopharmaceutical dispensing — questions we hear from Indian cyclotron teams
What manual step CRP eliminates for the operator, how it fits EU GMP Annex 1 Grade A dispensing, whether it dispenses multi-tracer sessions, and how the CRP + FLEX integrated supply fits an Indian cyclotron site.
Q.What manual step in a cyclotron radiopharmacy does the CRP dispenser eliminate?
Manual dispensing of PET radiopharmaceuticals requires an operator to draw each patient dose from a bulk vial into an individual syringe, verify activity on a dose calibrator, cap and label the syringe — repeated for every patient on the day list. At 511 keV activity, every one of those steps sits close to the operator hand and body, and human-error rates in activity measurement compound across the shift. CRP automates the full dispensing sequence — vial handling, syringe draw, activity measurement, capping, labelling — inside the dispensing hot cell. The operator sets up the run and the module dispenses the list.
Q.How does CRP fit EU GMP Annex 1 aseptic dispensing requirements?
EU GMP Annex 1 requires aseptic manufacturing steps to happen under Grade A airflow with continuous environmental monitoring. CRP runs inside a FLEX dispensing hot cell that provides the Grade A envelope; the automation itself is closed to the outside environment during the run, and every dispensing step is logged for the batch record. The GMP audit trail is generated automatically instead of hand-written.
Q.Which activity-measurement standard does CRP dispense against?
Each dispensed syringe is measured on an integrated dose calibrator against the site's NIST- or PTB-traceable calibration standard; the measured activity is logged to the batch record and printed on the syringe label. This is what the receiving nuclear-medicine department reads at patient injection time — the printed activity that matches the calibrator reading, at the calibration time on the label.
Q.Does CRP handle multi-tracer sessions (F-18 + Ga-68 + Lu-177)?
Yes. The dispensing sequence, syringe geometry and dose-calibrator settings are configurable per isotope; the module can dispense a morning F-18 FDG list, followed by a Ga-68 DOTATATE list, followed by a Lu-177 PRRT dispensing run — the internal cleaning cycle between isotopes prevents cross-line carry-over.
Q.How is CRP supplied and integrated in India?
CRP is distributed by Saxsons Group as an inside-cell automation module. The typical supply covers CRP + FLEX (the hot cell that hosts it) as an integrated package — one AERB import file, one commissioning cycle. Saxsons handles the CDSCO medical-device import registration and installation across the Indian cyclotron network.
CRP Radiopharmaceutical Dispensing System supplier in India — Saxsons Group
Saxsons Group has supplied cyclotron equipment to over 1,000 Indian hospitals since 1988. Every consignment of CRP Radiopharmaceutical Dispensing System ships with cold-chain logistics, AERB import documentation, CDSCO registration references and a Certificate of Analysis delivered before dispatch — the paperwork your radiation-safety and procurement teams need, pre-assembled.
- Nationwide delivery footprint — every metro and tier-2 city in India, scheduled to your treatment / procedure calendar.
- AERB & CDSCO documentation — import licence, radiation-safety paperwork and RSO briefing pre-assembled for the audit file.
- 40+ years in Indian oncology — long-standing supply relationships with AIIMS, Tata Memorial, and hundreds of tertiary-care centres.
- Single point of accountability — one purchase order, one delivery contact, one after-sales team across the whole product family.
Also supplied by Saxsons Group across India
Add automated F-18 dispensing to your cyclotron radiopharmacy
Contact Saxsons Group for pricing, FLEX + CRP integrated packages, demo arrangement, AERB import documentation and installation support for the CRP Compact / CRP Compact plus dispensing module.