Pre-treatment verification — IMRT/VMAT gamma analysis, log-file QA, 3D dose reconstruction. Curated daily from Europe PMC (PubMed + PMC + preprints) and OpenAlex — free-full-text link on each open-access paper.
Ambroa E, Gallego P, Pérez-Alija J, de la Cruz M et al.
BackgroundPatient-specific quality assurance (PSQA) in radiotherapy commonly relies on global gamma passing rate (GPR) metrics, which summarize delivery agreement as a single scalar value and therefor…
In helical tomotherapy (HT), the beam intensity is modulated by controlling the leaf open time (LOT) of a binary multileaf collimator (MLC), represented as sinograms. Comparing planned and recorded si…
Balasubramanian S, Anbalagan D, Thanasekar P, Agrawal R.
Our study aimed to perform a comprehensive end-to-end (E2E) dosimetric and geometric evaluation of the newly commissioned Varian Edge linear accelerator (LINAC) with the HyperArc™ VMAT system for mult…
Background/objectivesOnline adaptive radiotherapy (oART) re-optimizes treatment on the anatomy of the day, but automatically generated plans require dosimetric verification and dose-volume assessment.…
PurposePrevious studies have suggested that direct interaction between medical physicists and patients may improve patient understanding of radiation therapy and reduce treatment-related anxiety. Howe…
This study aimed to characterize the response and inter-system consistency of a high-resolution myQA SRS detector used for patient-specific quality assurance (PSQA) across different configurations of …
BackgroundReal-time multileaf collimator (MLC) adaptation is available on some helical tomotherapy treatment units. However, these systems are not supplied with software that facilitates the retrospec…
Stasinou D, Platoni K, Margaroni V, Zourari K et al.
BackgroundSingle-isocenter stereotactic radiosurgery enables efficient treatment of multiple brain metastases (SI-MBM SRS), but demands high geometric accuracy. Plan complexity metrics are increasingl…
St-Aubin J, Gutierrez A, Kinsey E, Stambaugh C et al.
This work of fiction is part of a case study series developed by the medical physics leadership academy (MPLA). It is designed to generate discussion of the managerial and leadership challenges medica…
Stereotactic body radiotherapy (SBRT) for liver metastases requires accurate dose calculation. The Monte Carlo (MC) algorithm in the Monaco treatment planning system (TPS) provides high dose-calculati…
Background: Volumetric modulated arc therapy (VMAT) for stereotactic body radiotherapy (SBRT) involves highly modulated dose distributions and steep dose gradients, increasing the importance of patien…
Sánchez-Artuñedo D, Campos-Domenech A, Reyes-López V, Matheos-Perez J et al.
PurposeSafety and quality assurance software in external beam radiotherapy may improve oncologic outcomes by enabling early detection of treatment delivery deviations. This work describes the clinical…
PurposeStereotactic arrhythmia radioablation (STAR) is a noninvasive treatment option for managing ventricular tachycardia (VT). Combined respiratory and cardiac motion requires management with large …
QA & dosimetry📖 Free full textPeer-ReviewedPubMedPhysica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) · 2026
Mastella E, Szilagyi KE, Perrine JS, Ferioli M et al.
Accurate dose verification is essential in stereotactic radiosurgery (SRS), where small fields and steep dose gradients may amplify uncertainties, especially with complex techniques like multitarget s…
Rahim Li F, Cardan RA, Pogue JA, Viscariello NN et al.
Accurate modeling of multi-leaf collimators is critical for dose calculation in stereotactic radiosurgery (SRS), where steep dose gradients and small target volumes amplify modeling uncertainties. Thi…
Mehmet Fazil Enkavi, Hasan Uysal, Kaan Oysul, Sait Şirin et al.
OBJECTIVE: To develop a high-spatial-resolution Cherenkov-excited fluorescence dosimetry system (CEFD) with rapid optical readout using quinine sulfate solution and evaluate its feasibility for small-…
To evaluate site-specific performance and complexity-dependent risk in patient-specific quality assurance for robotic radiosurgery using a two-dimensional array detector. A retrospective analysis was …
PurposeThis study aimed to evaluate the feasibility of fast Fourier transform (FFT) based spectral features for predicting volumetric modulated arc therapy (VMAT) gamma passing rates (GPRs) in virtual…
To develop a machine learning (ML)-based workflow for virtual patient-specific quality assurance (PSQA) to predict local gamma passing rates (GPRs) and QA pass/fail outcomes for Volumetric Modulated A…
QA & dosimetry📖 Free full textPeer-ReviewedPubMedRadiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2026
Brunner J, Albertini F, Bernardini GP, Bertschi S et al.
Background and purposeClinical implementation of online adaptive proton therapy requires rigorous testing of all facility-specific components. This work aimed to develop a multi-purpose phantom-based …
The objective of this study is to perform an end-to-end (E2E) technical validation of a total body irradiation (TBI) workflow using an anthropomorphic phantom, integrating simulation, treatment planni…
BackgroundVolumetric modulated arc therapy (VMAT) enables highly conformal pelvic dose delivery, but its clinical benefit depends on agreement between the Treatment Planning System (TPS) calculation a…
Mico S, Hermida-López M, Ramos-Albiac M, Pié-Padró S et al.
Background and purposeTotal body irradiation (TBI) is a standard component of conditioning regimens for pediatric patients with acute lymphoblastic leukemia (ALL) undergoing hematopoietic stem cell tr…
A transition from the dose-to-water algorithm AAA to the dose-to-medium algorithm Acuros XB (AXB) presents challenges for comparison with measurements made in the dose-to-water calibrated ArcCHECK. Th…
ObjectiveTo develop a fast and accurate physics-informed framework for real-time three-dimensional dose reconstruction directly from machine delivery beams for adaptive radiotherapy and intra-fraction…
ObjectiveThe precision of modern radiotherapy hinges on the dynamic sculpting of dose by multi leaf collimators (MLCs). This study introduces a physics informed, interpretable framework that models ML…
Chevillard C, Blanchet M, Mella C, Sauvinet R et al.
BackgroundMagnetic resonance-guided radiotherapy using 1.5 T MR-LINAC systems introduces specific constraints for patient-specific quality assurance (PSQA), requiring MR-compatible dosimetric devices …
BackgroundHyperArc is an effective technique for treating multiple small brain metastases using high-definition, precise radiation. However, the small size of individual lesions makes treatment vulner…
ObjectivesElectronic portal imaging devices (EPID) are well suited to radiotherapy in-vivo dosimetry (IVD), but limited guidance remains a barrier to routine clinical use. This SunCHECK (Sun Nuclear C…
García-Garduño OA, Ávila-Muñoz Y, Gamboa-deBuen I, Lárraga-Gutiérrez JM.
Radiochromic films are widely used in radiotherapy dosimetry for their high spatial resolution and near-water-equivalence. Nonetheless, these films are frequently purchased in bulk, leading clinical d…
CyberKnife stereotactic radiosurgery (SRS) treatment of multiple brain metastases (MBM) using fixed cone collimation is well established. This study aims to rigorously evaluate the commissioning of MB…
Accurate dose calculation in spatially fractionated radiotherapy (SFRT) is challenging because highly heterogeneous dose distributions and charged-particle disequilibrium can reduce the accuracy of fa…
QA & dosimetryPeer-ReviewedPubMedPhysica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) · 2026
Reducing the lung dose rate significantly decreases the risk of toxicity in high-dose total-body irradiation (TBI). This study investigated the feasibility of delivering Volumetric Modulated Arc Thera…
Abstract Background Cone-beam computed tomography (CBCT) is increasingly being integrated into adaptive radiotherapy workflows; however, its use for accurate dose calculation has historically been lim…
QA & dosimetryPeer-ReviewedPubMedPhysica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) · 2026
Outsikas K, Patatoukas G, Chalkia M, Zourari K et al.
To investigate parameters systematically associated with low Gamma Passing Rate (GPR) values in Volumetric Modulated Arc Therapy (VMAT) technique in head and neck radiotherapy plans and to evaluate wh…
To predict and classify the gamma passing rate (GPR) for patient-specific quality assurance (PSQA) in VMAT using a deep learning approach based on accelerator dynamic log files. Dynamic log files of 4…
This study aims to evaluate the impact of two dose reconstruction techniques, standard and composite, on gamma passing rates (GPRs) during pre-treatment quality assurance of large-field pelvic RapidAr…
BackgroundPatient-specific quality assurance (PSQA) plays a pivotal role in intensity-modulated radiotherapy (IMRT) to ensure accurate dose delivery. However, conventional measurement-based PSQA appro…
BackgroundRunning VMAT plan-complexity surveillance directly inside an oncology information system (OIS) makes it practical to monitor plan quality across a large, multi-linac program. Complexity metr…
IntroductionGuidelines on how to perform patient-specific quality assurance (PSQA) in stereotactic radiotherapy (SRT) are currently not available. In this context, guidelines for modulated techniques …
Bartolucci L, Richert A, Azhar HE, Jarnet D et al.
PurposePatient-specific quality assurance (PSQA) for VMAT treatments represents a significant workload. This study presents an integrated approach combining plan complexity metrics with statistical pr…
Stereotactic radiotherapy on CyberKnife demands high precision in dosimetry due to the involvement of small-field treatments. This study addresses the geometric and dosimetric limitations of conventio…
AimThis study aimed to evaluate the Halcyon-E O-ring gantry linear accelerator, which lacks non-coplanar beam delivery capability, for single-fraction stereotactic radiosurgery (SRS). The validation p…
BackgroundVolumetric Modulated Arc Therapy (VMAT), as an advanced radiotherapy technique places higher demands on quality assurance (QA) during treatment planning. Although multiple verification syste…
Schiebl M, Trnková P, Heilemann G, Jindráková M et al.
This study introduces a probabilistic framework for patient-specific quality assurance (PSQA) in volumetric modulated arc therapy (VMAT), using gamma pass rates obtained from both measurement-based an…
Dufreneix S, Essers M, Aspradakis MM, Wegener S et al.
Background and purposeAs treatment planning and delivery systems nowadays have the capability to simulate and realise increasingly complex irradiation geometries, quality assurance programs need to be…
Background and purposeA novel gimbal-mounted linear accelerator (linac) enables off-axis beam delivery. This study was aimed at commissioning an expanded-field radiation technique using a gimbal-mount…
Background Volumetric Modulated Arc Therapy (VMAT) is a highly conformal radiotherapy technique that enables precise tumor irradiation while sparing surrounding healthy tissue. However, the high techn…
Background and purpose The American Association of Physicists in Medicine Task Group 307 (AAPM TG-307) recommends validation of electronic portal imaging device (EPID) patient-specific quality assuran…
Everard AJ, Santo RJ, Borman PTS, Uijtewaal P et al.
Background and purpose The precision of Positron Emission Tomography (PET)-guided radiotherapy may be compromised by motion. To address this, we demonstrated the feasibility of a motion-robust PET-to-…
PurposeWe conducted a multicenter study on single-isocenter multitarget stereotactic radiosurgery to dosimetrically assess end-to-end test results and identify approaches and techniques influencing sp…
May L, Baeza-Ortega JA, Hussein M, Porter S et al.
BackgroundThere is large variability in patient specific quality assurance (PSQA) devices, techniques and protocols used clinically in radiotherapy. The SEAFARER methodology enables centres to evaluat…
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