Radiotherapy QA · Literature Radar
MR-linac clinical and physics evidence — on-table adaptation, gating, daily-online plan adapt. Curated daily from Europe PMC (PubMed + PMC + preprints) and OpenAlex — free-full-text link on each open-access paper.
Xiao F, Delopoulos N, Wahl N, Volz L et al.
PurposeAccurate dose calculation is a fundamental component of modern radiotherapy, enabling precise tumor irradiation while sparing surrounding healthy tissue. With the increasing adoption of magneti…
Leblanc J, Terlizzi M, Lapierre A, Le Guévelou J.
Adaptive radiotherapy has emerged as a promising strategy to improve the precision of prostate cancer treatment by accounting for daily anatomical variations. Recent technological advances have enable…
Kassardjian AA, Maraghechi B, Shi C, Ai H et al.
Purpose/objectivesOptimal implementation of gadoxetate disodium injection (GDI) in liver-directed MR-guided online adaptive radiotherapy (MRgART) remains poorly characterized. Herein, we evaluated the…
Birring E, Zhao Y, Lim TY, Mohammedsaid M et al.
PurposeMagnetic resonance (MR) -guided online adaptive radiotherapy requires skill in online adaptive treatment planning. The aim of this study was to demonstrate that radiation therapists, with appro…
Gao Y, Hsu E, Pham D, Skinner L et al.
PurposeConventional liver stereotactic ablative radiotherapy (SABR) typically requires a CT simulation visit followed by multiple treatment fractions, which can increase patient burden and limit acces…
Poeta S, Gulyban A, Paquier Z, Michel M et al.
PurposeTo quantify inter-physician contouring variability and evaluate its dosimetric impact in pancreatic ductal adenocarcinoma (PDAC) patients treated with daily online adaptive MR-guided stereotact…
Zhu M, Jen JH, Hyer DE, Trentadue TP et al.
Magnetic resonance-guided radiotherapy (MRgRT) enables real-time tracking of tumor and organ motion for more precise radiation delivery. However, existing clinical tracking software struggles with hig…
Williams B, Sandoughdaran S, Chick J, Dunlop A et al.
IntroductionBladder MRI-guided online adaptive radiotherapy (MRIgART) has enabled a reduction in planning target volume (PTV) margins, reducing normal tissue irradiation. Yet, further margin reduction…
Munoz L, Alinaghi-Zadeh R, Gibson S, Jelen U et al.
MRI-guided radiotherapy introduces unique quality assurance (QA) requirements due to magnetic field effects on dose delivery, imaging-dependent workflows, adaptive planning and system specific conside…
Smyczyńska U, Nowicka Z, Doyle P, Kang H et al.
IntroductionUrinary toxicities are common following prostate radiotherapy and can impair quality of life. New biomarkers are needed that can predict the risk of urinary toxicity following MRI guided s…
Kretzschmar L, Wallimann P, Obergfell LM, Tanadini-Lang S et al.
Serial MRI during radiotherapy may enable early response assessment and guide adaptive treatment strategies; however, data on intratreatment volumetric changes remain limited. We herein report results…
Wang Z, Wang S, Liu N, Guan Q et al.
BackgroundOnline adaptive radiotherapy (ART) employs modalities like CBCT, CT, and MRI. For abdominal malignancies, MRI stands out with superior soft-tissue contrast, no ionizing radiation, and functi…
McCullum L, Subashi E, Mulder SL, Taylor BA et al.
BackgroundThe extraction of quantitative biomarkers on the MR-Linac, which have been shown to be promising in the head and neck, remains a significant challenge due to the strict time constraints.Purp…
Hartfelt PB, Bisgaard ALH, Ejlsmark MW, Bahij R et al.
PurposeThis prospective single-center cohort study evaluated outcomes and toxicity after ablative stereotactic magnetic resonance imaging (MRI)-guided adaptive radiation therapy (SMART) in patients wi…
Vat K, Stanescu T.
Objective.Integrating medical linear accelerators and magnetic resonance imaging (MRI) scanners for MRI-guided radiotherapy (MRgRT) is complicated by mutual magnetic field coupling, making efficient f…
McHugh DJ, Swinton M, Hart CA, Martinez DS et al.
PurposeQuantitative MRI biomarkers require validation before being used to assess treatment response or inform biological image-guided adaptive radiotherapy on MRI-linacs. This work contributes to the…
Rezzoug M, Oulhouq Y, Hamzaoui O, Zerfaoui M et al.
This study investigates the influence of magnetic field orientation (Ox, Oy, Oz) and strength (0-3 T) on percentage depth dose (PDD) and dose profile parameters for 6 MV clinical photon beams using Mo…
Zhou X, Huang N, Fang Z, Tang J et al.
BackgroundAccurate quantification of intravoxel incoherent motion (IVIM) parameters on the magnetic resonance linear accelerator (MR-Linac) is challenging due to low signal-to-noise ratio and time con…
Paunoiu A, Fritsak M, Gabryś HS, Christ SM et al.
Background and purposeMagnetic resonance-guided radiotherapy (MRgRT) offers high-quality soft tissue contrast and treatment monitoring, supporting longitudinal radiomics analysis. We investigated trea…
Hilgers GC, Woodings SJ, Foppen TA, Wolthaus JWH et al.
Background and purposeMagnetic resonance-guided radiotherapy systems require comprehensive quality assurance (QA) programs to ensure safe and precise treatment delivery. This study evaluates the long-…
Park S, Wang P, Paik J, Pennell R et al.
Background and purposeTo investigate whether an AI-based method can detect subtle inter-fraction changes in MR-Linac images acquired during radiotherapy and explore the broader potential of MR-Linac i…
Linden SML, Philippens MEP, Rijken JA, Brand E et al.
IntroductionUltra-hypofractionation for early-stage glottic cancer reduces the number of hospital visits, but requires precise delivery to minimize the risk of radiation-induced toxicity. Magnetic Res…
Wang X, Lim TY, Wang H, Dabaja BS et al.
A patient presenting with stage I follicular lymphoma was dispositioned for a definitive and curative radiation treatment. The tumor had significant daily movement, as much as 3.83, 3.26 and 12.42 cm …
Takahashi Y, Takahashi N, Kageyama S, Tanaka S et al.
BackgroundHydrogel spacers are widely used in radiotherapy for localized prostate cancer to reduce the rectal dose. While generally safe, acute anatomical changes in the prostate gland itself, specifi…
Tan D, Edwards L, Byrne HL, Liang T et al.
We present a case series of four patients with five splenic metastases treated with stereotactic body radiation therapy (SBRT) using a 1.5-T Unity (Elekta AB, Stockholm, Sweden) magnetic resonance lin…
Tam KH, Jogi S, Sobremonte A, Ohrt JD et al.
Purpose: To quantify the dosimetric effect of residual intrafraction motion during gated MR-guided prostate stereotactic body radiotherapy with simultaneous integrated boost to the dominant intraprost…
Edwards L, Tan H, Rahim K, Leong E et al.
In recent years, cervical cancer incidence has been on the decline in Australia, likely due to the HPV vaccination and an improved screening programme. However, an estimated 900 new cases will be diag…
Peterson JS, Goodchild S, Jain S, Bryant JM et al.
BackgroundGastroenteropancreatic neuroendocrine tumors (GEP-NETs) are an indolent subset of neuroendocrine neoplasms with a propensity to metastasize. In the case of oligoprogression, locoregional the…
Cooper S, Brennan VS, Alongi F, Chick J et al.
BackgroundLocal recurrence in prostate cancer (PCa) after radical radiotherapy has become increasingly prevalent in the era of next-generation imaging. Meta-analyses suggest a favourable adverse event…
Betancourt Tarifa AS, Verheij M, Monshouwer R, Hermans JJ et al.
Background and purposeReal-time tumor tracking on cine magnetic resonance imaging (cine-MRI) enables intra-fraction motion management in magnetic resonance-guided radiotherapy. Pipelines often rely on…
Marisa Cobanaj, Franciska Lebbink, Sergej Schneider, Emilia Louisa Ernestine Schäfer et al.
OBJECTIVE: Integrating in-beam magnetic resonance imaging (MRI) with proton therapy (PT) introduces magnetic fields (MFs) that affect proton beam transport and therefore require accurate incorporation…
Wang A, Fang J, Tan M, Li Y et al.
MR-guided radiotherapy (MRgRT) combines high-contrast MRI, online adaptation, and radiation delivery in a single treatment workflow. The static magnetic field, however, changes the transport of second…
Zhang J, Shi S, Wu J, Tan Z et al.
Oligometastatic pancreatic ductal adenocarcinoma (PDAC) may benefit from aggressive multidisciplinary therapy, yet the role of stereotactic body radiotherapy (SBRT) remains controversial and framework…
Dudas D, Blöcker TJ, Palacios MA, Wei C et al.
Background and purposeThis study presents a novel workflow for automated gross tumor volume (GTV) adaptation in online adaptive magnetic resonance imaging (MRI)-guided radiotherapy using promptable se…
Coskun M, Petersson JS, Wetterstedt SA, Brynolfsson P et al.
Magnetic resonance imaging (MRI) offers superior soft-tissue contrast and MRI-only radiotherapy (RT) eliminates uncertainties associated with computed tomography (CT)-to-MRI image registration. An MRI…
Sekkat H, Khallouqi A, Hammougua O, Halimi A et al.
Shabbir R, Zakacz A, Sivakaran R, Osorio EV et al.
BackgroundDaily adaptive magnetic resonance (MR)-guided treatment changes delivered dose distributions, making cumulative dose uncertain. This work assessed the feasibility of exploring potential rela…
Li C, Rusu D, Sultan R, Bagher-Ebadian H et al.
BackgroundManual organ-at-risk (OAR) delineation takes 20-40 min per case, a major bottleneck within the 50-90 min treatment window of abdominal MR-guided adaptive radiotherapy (MRgRT). Most deep lear…
Ocanto A, Teja M, Gonsalves D, Vásquez W et al.
Magnetic resonance-guided radiotherapy (MRgRT) delivered with MR-linac technology represents a major advance in lung cancer radiotherapy, enabling daily online adaptive planning based on high-quality …
Cui S, Chan MF, Zheng D.
Online adaptive radiotherapy (OART) modifies treatment plans using anatomy-of-the-day imaging, but successful clinical implementation depends on automated planning strategies that can generate high-qu…
Shay O, Solis D, Aire M, Schneider C et al.
BackgroundAbdominal compression (AC) using a belt-based system is widely employed in radiation therapy to limit respiration-induced target motion for abdominal and hepatic malignancies. While AC has d…
Herrera RA, Unsri S, Mittauer KE, Kotecha R et al.
Purpose: While magnetic resonance-guided radiation therapy (MRgRT) may provide significant clinical advantages, delivery times tend to be longer than other radiation therapy (RT) modalities and publis…
Schneider M, Eberhardt T, Gani C, Fischer P et al.
Background and purposeNeural networks promise fast dose modelling with high accuracy for challenging situations like magnetic resonance imaging (MRI)-guided radiotherapy. As they are data-driven, fail…
Leeman JE, Droznin AD, Dwyer CD, Shin KY et al.
Five to 7 weeks of whole-larynx radiation (RT) is standard for treatment of early-stage glottic cancer. Previous studies evaluated CT-guided hypofractionated/SBRT treatment to a smaller volume. Magnet…
Georgas K, Vagenas TP, Vezakis IA, Kakkos I et al.
Magnetic Resonance Imaging (MRI) is a key modality in cancer treatment, providing high soft tissue contrast for the visualization of tumors and internal anatomy. Radiotherapy, which is widely used in …
Amanda Östensson, Joakim Jonsson
BACKGROUND: There is an increasing use of magnetic resonance imaging (MRI) for segmentation of target volumes and organs at risk due to superior soft tissue contrast compared to computed tomography (C…
Marc Vincent Barcelona, Noelia Sanmamed, Enrique Gutierrez Valencia, Alejandro Berlín et al.
We report early toxicity outcomes after institutional implementation of prostate SBRT using 42.7 Gy in seven fractions delivered with either MR-guided adaptive SBRT (MRgSBRT) or CT-guided non-adaptive…
Kai Yuan, Matthew M. Cheung, Louis Lee
BACKGROUND: Patient-Specific Quality Assurance (PSQA) for Elekta Unity MR-Linac treatments delivered under Comprehensive Motion Management (CMM) is challenging because beam gating, unexpected interrup…
Nishitani M, Okamoto H, Chang W, Kuwahara J et al.
Current quality assurance phantoms often lack MR signal, deformability, or real-time dosimetry capability, limiting comprehensive end-to-end evaluation for MR-guided online adaptive radiotherapy (MRgO…
Foysal Ahmed
Magnetic resonance imaging (MRI) provides excellent soft tissue contrast without ionizing radiation, making it a strong alternative to computed tomography (CT) in medical imaging workflows. However, C…
Nicholas Castellano
Magnetic resonance guided radiation therapy (MRgRT) combines magnetic resonance imaging (MRI) and radiation therapy to enable the visualization of anatomy in real time during treatment. The presence o…
S Cooper, H Akhiat, S Alexander, F Alongi et al.
Abstract Background Prostate volume changes during radiotherapy may compromise target coverage. We quantified longitudinal swelling across longer fractionation (≥15 fractions)(LFRT) and stereotactic b…
Maziero D, Cao M.
Magnetic resonance imaging (MRI) is increasingly integrated into radiation oncology through dedicated MRI simulators and MR guided radiotherapy systems, improving target delineation and enabling adapt…
Qian X, Shao HC, Deng J, Dai Y et al.
Existing volumetric MRI techniques are constrained by the trade-off between acquisition time and image quality, limiting accuracy in motion-impacted sites such as the liver. To enable fast, high-quali…
Eric D. Brass
Problems: Adaptive radiotherapy requires clinically practical methods for responding to patient-anatomy changes that occur between the original planning images and the day of treatment delivery. Regis…
Yunxiang Li, Yan Dai, Yen‐Peng Liao, Jie Deng et al.
Background: Magnetic resonance imaging-guided linear accelerators (MR-Linacs) allow diffusion-weighted imaging (DWI) to be acquired at every treatment fraction, but converting these low-signal-to-nois…
Vaitheeswaran R.
Mean apparent diffusion coefficient (ADC) is the dominant quantitative endpoint in MR-guided radiotherapy response assessment. We prove that for any symmetric local coupling between tumour sub-regions…
Tariq H, Afzal T, Khan A.
Oligometastatic disease (OMD) and oligoprogression are clinically actionable states in which local treatment of limited tumour burden can prolong disease control for selected patients. Randomised phas…
Rahnama N, Tanadini-Lang S, Joy VN, Elter AS et al.
Abstract Background MRI-based autocontouring has the potential to improve radiotherapy planning and adaptive workflows by reducing contouring time while maintaining clinical quality. We evaluated a pr…
Koduri S, Barbee D, Oh C, Sherman T et al.
The purpose of this study is to explore whether spacer hydrogel morphology changes during the course of stereotactic body radiation therapy (SBRT) radiation to the prostate. A total of 198 patients at…
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