Munoz L, Alinaghi-Zadeh R, Gibson S, Jelen U et al.
MRI-guided radiotherapy introduces unique quality assurance (QA) requirements due to magnetic field effects on dose delivery, imaging-dependent workflows, adaptive planning and system specific conside…
Fidelis ALE, Batista DVS, Cardoso SC, da Rosa LAR.
External beam radiation therapy (EBRT) is widely used for uveal melanoma to preserve the eye and achieve effective tumor control. However, late side effects remain a concern, reinforcing the need for …
PurposeThe study evaluated the image quality of the cone beam computed tomography (CBCT) system on Varian TrueBeam linear accelerators with HyperSight (TB-HS) and compared it with the standard TrueBea…
Tsuno H, Sasaki K, Sasaki R, Matsubayashi F et al.
PurposeUser-derived electrometer calibration factors (kelec, user) have been proposed as a practical approach for electrometer quality assurance in radiotherapy dosimetry. However, the contribution of…
BackgroundBeam diagnostic systems are essential for the development and quality assurance of ultra-high dose rate (UHDR) radiation sources to enable reliable delivery of FLASH radiotherapy (RT). Criti…
Tamura M, Nishimura Y, Matsuura T, Inosaka Y et al.
BackgroundA new preconfigured CyberKnife system was introduced to improve the SRS/SBRT commissioning efficiency. The vendor provides a reference beam data set, termed "beam data model (BDM)", and reco…
PurposeTo develop and evaluate a water-profile-based (WP) calibration method for two-dimensional (2D) ionization chamber arrays used in medical linear accelerator (linac) quality assurance (QA), and t…
This study aimed to evaluate the beam data of Elekta stereotactic radiosurgery (SRS) cone collimators for 6MV and 6MV flattening filter-free (6MVFFF) beams and to assess the feasibility of implementin…
BackgroundCone-beam computed tomography (CBCT) is integral to image-guided radiation therapy and increasingly used for adaptive radiotherapy and CBCT-based dose calculation. Conventional kV-CBCT syste…
BackgroundState regulatory inspections of radiation-producing treatment equipment combine a review of quality assurance and regulatory records with direct verification of facility and safety systems. …
To characterize routine kV cone-beam CT (CBCT) imaging dose in image-guided radiotherapy (IGRT) and to derive indication-specific local benchmark values using and DLP for clinical protocol optimizatio…
The increasing clinical use of stereotactic radiosurgery, stereotactic body radiotherapy and intensity-modulated radiotherapy has heightened the need for accurate small-field dosimetry. In sub-centime…
Background: Delivery of ultra-high dose rate radiation at mean dose rates > 40 Gy/s, also known as FLASH, shows great promise in widening the therapeutic window by decreasing the normal tissue complic…
Ultra-high dose rate (FLASH) radiotherapy has demonstrated promising normal tissue sparing in preclinical studies; however, the lack of standardized dosimetry, commissioning, and quality assurance (QA…
O. El mouden, H. Sekkat, A. Bannan, R. El Baydaoui et al.
Accurate characterization of the tissue–maximum ratio (TMR) is important for beam modelling and dosimetric verification, particularly for flattening-filter-free (FFF) beams and non-reference fields. T…
This study provides a review of recent publications on different quality control (QC) techniques for radiotherapy linear accelerators (linacs). QC in radiotherapy is essential to ensure patient safety…
Pisaturo O, Ghandour S, Miéville F, Pitteloud N et al.
ObjectiveAccurate modelling of dose deposition remains a central challenge in external beam radiotherapy, particularly for modern treatment systems involving complex beam configurations and magnetic f…
BackgroundSurface-guided radiation therapy (SGRT) has been increasingly adopted in modern radiotherapy, enabling radiation-dose-free, marker-free patient positioning with high accuracy. A novel SGRT s…
PurposeThis study provides a comprehensive evaluation of the newly implemented electron Monte Carlo dose calculation algorithm in the commercial treatment planning system, uTPS. It investigates the pe…
Pantelis E, Moutsatsos A, Sideri L, Archontakis P et al.
BackgroundThe CyberKnife™ system requires extensive beam data acquisition across multiple collimation systems. The CyberComm™ framework integrates a linac output tuning procedure with a hybrid Golden …
QA & dosimetryPeer-ReviewedPubMedPhysica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) · 2026
PurposeTo evaluate a multipurpose MZ CUBE-based workflow for selected CBCT QA endpoints, including translational IGRT-relevant geometric verification and core image quality (IQ) assessment, across thr…
QA & dosimetryPeer-ReviewedPubMedPhysica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) · 2026
PurposeThis study evaluates the feasibility, dosimetric optimization, and delivery efficiency of c_arm linac-based and TomoTherapy-based Lattice Radiotherapy (LRT) across head and neck, thoracic, and …
García-Garduño OA, Ávila-Muñoz Y, Gamboa-deBuen I, Lárraga-Gutiérrez JM.
Radiochromic films are widely used in radiotherapy dosimetry for their high spatial resolution and near-water-equivalence. Nonetheless, these films are frequently purchased in bulk, leading clinical d…
Accurate dose calculation in spatially fractionated radiotherapy (SFRT) is challenging because highly heterogeneous dose distributions and charged-particle disequilibrium can reduce the accuracy of fa…
The novel HyperSight cone-beam CT (CBCT) system (Varian Medical Systems, Siemens Healthineers, Palo Alto, USA) provides image quality comparable to native CT and offers advantages for contouring in on…
Background: Independent end-to-end verification of adaptive radiotherapy on MR-Linac systems is limited by the lack of patient-specific phantoms able to reproduce imaging and dosimetric properties fro…
ObjectiveReal-time tumor-tracked radiation therapy has the potential to enhance geometric treatment accuracy by adapting radiation delivery to tumor motion during irradiation. The multi-leaf collimato…
Gantry angle inaccuracies during treatment delivery affect the dose distribution received by the patient. These inaccuracies may arise from stretching of the gantry belt, leading to hysteresis in the …
BackgroundThe MR-Linac enables adaptive radiotherapy using MRI guidance. Volumetric modulated arc therapy (VMAT) has been shown to be feasible on the MR-Linac and offers many advantages, but commissio…
BackgroundStatistical Process Control (SPC) has gained increasing interest in radiotherapy Quality Assurance (QA), particularly following recommendations from American Association of Physicists in Med…
Background and purposeA novel gimbal-mounted linear accelerator (linac) enables off-axis beam delivery. This study was aimed at commissioning an expanded-field radiation technique using a gimbal-mount…
PurposeThis study aimed to commission the AlignRT inBore system in Ethos/Halcyon linear accelerator (Linac) systems for surface-guided radiotherapy (SGRT), including developing a soft collision qualit…
PurposeThis study quantifies isocenter and off-axis geometric uncertainties using MultiMet Winston-Lutz (WL) tests to optimize gross tumour volume (GTV)-to-PTV (planning target volume) margin for sing…
BackgroundElectronic portal imaging device (EPID)-based in vivo dosimetry (IVD) has attracted considerable interest in recent years. Nevertheless, the limited detection area of conventional EPID syste…
Gonçalves Jorge P, Geyer R, Kinj R, Schiappacasse L et al.
BackgroundThe FLASH effect, induced by ultra-high dose rate (UHDR) irradiations, offers the potential to spare normal tissue while effectively treating tumors. It is important to achieve precise and a…
Purpose This study aims to assess the feasibility of implementing a hypofractionated radiation therapy (HFRT) program at the Oncology Directorate of Komfo Anokye Teaching Hospital in Ghana, addressing…
Introduction Superficial x-rays (50-100 kVp) are used for treating non-melanoma skin cancer and intraoperative radiation therapy (IORT). At these energies, the photoelectric effect significantly incre…
Purpose This study evaluates a novel cone-beam computed tomography (CBCT) imaging solution integrated onto a conventional C-arm linear accelerator (linac) with increased gantry speed. The purpose is t…
Saini J, Erickson DPJ, Vander Stappen F, Ruth M et al.
Background This manuscript describes modifications to a pencil beam scanning (PBS) proton gantry that enables ultra-high dose rates (UHDR) irradiation, including treatment planning and validation. Met…
Stereotactic body radiotherapy (SBRT) treatment of oligometastatic lesions via single-isocenter/multi-target (SIMT) plan is more efficient than using multi-isocenter/multitarget SBRT. This study quant…
Purpose This article describes our experience in implementation of superficial radiation therapy (SRT) using SRT-100 Vision™ for non-melanoma skin cancer. Methods Following the American Association of…
Juvkam IS, Zlygosteva O, Arous D, Galtung HK et al.
Radiotherapy (RT) of head and neck (H&N) cancer is known to cause both early- and late-occurring toxicities. To better appraise normal tissue responses and their dependence on treatment parameters suc…
Purpose The recently worldwide standard measurement of electron beam reference dosimetry include the International Atomic Energy Agency (IAEA) Technical Report Series (TRS)-398 and Association of Phys…
Tyagi N, Subashi E, Michael Lovelock D, Kry S et al.
Introduction To investigate the impact of partial lateral scatter (LS), backscatter (BS) and presence of air gaps on optically stimulated luminescence dosimeter (OSLD) measurements in an acrylic minip…
Purpose The goal of this work was to develop and test nontoxic electron collimation technologies for clinical use. Methods Two novel technologies were investigated: tungsten-silicone composite and 3D …
Purpose A new medical linear accelerator (linac) platform integrated with helical computed tomography (CT), the uRT-linac 506c, was introduced into clinical application in 2019 by United Imaging Healt…
Moeckli R, Gonçalves Jorge P, Grilj V, Oesterle R et al.
PurposeTo present the acceptance and the commissioning, to define the reference dose, and to prepare the reference data for a quality assessment (QA) program of an ultra-high dose rate (UHDR) electron…
Over the last few years, magnetic resonance image-guided radiotherapy systems have been introduced into the clinic, allowing for daily online plan adaption. While quality assurance (QA) is similar to …
The era of real-time radiotherapy is upon us. Robotic and gimbaled linac tracking are clinically established technologies with the clinical realization of couch tracking in development. Multileaf coll…
PurposeIn this study, procedures were developed to achieve efficient reversible conversion of a clinical linear accelerator (LINAC) and deliver ultrahigh-dose-rate (UHDR) electron or conventional beam…
PurposeThis prospective study is, to our knowledge, the first report of daily adaptive radiation therapy (ART) for head and neck cancer (HNC) using a 1.5T magnetic resonance imaging-linear accelerator…
Snyder JE, St-Aubin J, Yaddanapudi S, Boczkowski A et al.
MR image-guided radiotherapy has the potential to improve patient care, but integration of an MRI scanner with a linear accelerator adds complexity to the commissioning process. This work describes a …
Purpose Consistency between different international quality assurance groups is important in the progress toward similar standards and expectations in radiotherapy dosimetry around the world, and in t…
PurposePreclinical studies using a new treatment modality called FLASH Radiotherapy (FLASH-RT) need a two-phase procedure to ensure minimal uncertainties in the delivered dose. The first phase require…
Granville DA, Sutherland JG, Belec JG, La Russa DJ.
The use of treatment plan characteristics to predict patient-specific quality assurance (QA) measurement results has recently been reported as a strategy to help facilitate automated pre-treatment ver…
Tijssen RHN, Philippens MEP, Paulson ES, Glitzner M et al.
BackgroundMagnetic Resonance linear accelerator (MR-linac) systems represent a new type of technology that allows for online MR-guidance for high precision radiotherapy (RT). Currently, the first MR-l…
PurposeTo report the feasibility, accuracy, and reliability of volumetric modulated arc therapy (VMAT)-based total-body irradiation (TBI) treatment in patients with acute myeloid leukemia (AML) or acu…
Lovo EE, Campos FJ, Caceros VE, Minervini MH et al.
Introduction The objective is to report the dosimetry and safety profiles of the first fully automatized rotating gamma ray unit for intracranial radiosurgery in America. Methods Dosimetry tests were …
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