Hot-Lab QC · Literature Radar
Hot-cell and dispensing-bench shielding — fume hood vs laminar flow, β/γ hybrid for Lu-177 / Y-90 work. Curated daily from Europe PMC (PubMed + PMC + preprints) and OpenAlex — free-full-text link on each open-access paper.
Ramos-Membrive R, Gil-Viciano I, Saldaña P, Maymó-Garrido S et al.
PurposeEnsuring patient and staff safety in nuclear medicine requires robust quality assurance and radiation protection systems. Radiopharmacists (RPhs) and medical physicists (MPs) play complementary…
Poonak K, Sopapan P, Thongkuam P, Sureeyaphan M et al.
Occupational radiation protection in nuclear medicine is challenged by ambient radiation fields that vary both spatially and temporally. This variability arises from routine radiopharmaceutical handli…
Tsuchiya J, Narita T, Anzai T, Koyama S et al.
Objective¹⁷⁷Lu is an approved radionuclide for targeted radionuclide therapy (TRT), first established with ¹⁷⁷Lu-DOTATATE for neuroendocrine tumors, and subsequently with PSMA-targeted therapy. The wi…
Marshall SK, Tepnarin P, Wattanaphonpinich W, Atsawasetthini W.
Lead-free polymer composites containing high-atomic-number fillers are promising alternatives to conventional lead shielding for nuclear medicine applications. In this study, Bi₂O₃-, WO₃-, and hybrid …
Zemmouri SY, Ferradji F, Chakouri M, Nebchi EM.
ObjectivesHospital radiopharmacy plays a central role in ensuring the quality, safety and regulatory compliance of radiopharmaceuticals used for diagnostic and therapeutic purposes. Given the complexi…
Lancova L, Kracmerova T.
Somatostatin receptor therapy (SSRT) with [177Lu]Lu-oxodotreotide is an established treatment for metastatic neuroendocrine tumours. However, radiation protection guidelines for patients with stomas r…
Kollaard R, Albiniak Ł, Cherbuin N, Dabin J et al.
Despite the increased use of177Lu in nuclear medicine (NM) over the last 10 years, the knowledge of the actual exposure of the extremities due to manipulation of this pharmaceutical is limited. The pu…
Alam R, Hasnat A, Masumbillah M, Zohra FT et al.
The commissioning of medical cyclotrons necessitates a thorough assessment of radioactive waste management systems, operational protocols, and radiological safety. Significant neutron and gamma radiat…
Rowley LM, Pickles C, Hodgson K, Kallioinen SE et al.
PurposeTo evaluate the radiation protection requirements for a UK first specimen PET-CT scanner, the AURA10 (Xeos, Ghent), as assessed through a clinical trial investigating its use for intra-operativ…
Murthy SVR, Sricharan KB, Raju GJN.
BackgroundRadioiodine-131(I-131) is widely used in the treatment of thyroid diseases. Despite its therapeutic advantages, working with unsealed sources such as I-131poses risk of airborne contaminatio…
Katzdobler L, Delker A, Giussani A, Hürkamp K et al.
The radiopharmaceutical 223Ra-dichloride (Xofigo®) has been approved for palliative treatment of metastatic castration-resistant prostate cancer. During the treatment and caregiving, patients who rece…
Bonardel G, Vuillez JP.
Nuclear medicine is a diagnostic and therapeutic medical specialty based on the administration of radiopharmaceuticals emitting ionizing radiation (IR). In this context, healthcare professionals are e…
Royer CJ, Gilmore D.
¹⁸F-FDG, widely used in PET imaging, produces high-energy 511-keV annihilation photons that pose radiation exposure risks in radiopharmaceutical preparation and handling areas, or hot labs. Understand…
Thomson WH, Burmiston J, Thompson-Peters JD, O'Brien J et al.
ObjectivesTo gauge the views of UK nuclear medicine staff on a skin contamination incident of 500 mSv from Tc-99m and Ra-223 (an alpha source).MethodsAn anonymous questionnaire asked staff their conce…
Dang P, Feng Z, Yang X, Cao X et al.
BackgroundThe handling of non-sealed radiopharmaceuticals poses significant risks of occupational exposure and radioactive contamination. With rapid growth in demand, an increasing number of workers a…
Jaramillo-Garzón W, Díaz-Martínez LC.
The objective of this work was to evaluate the radiation exposure received by workers in the nuclear medicine department of a private hospital in Bogotá, Colombia, during the period 2022-2023. The Hp …
Kebede MT, Dawud JE, Kejela BT, Gannamo MP et al.
BackgroundMedical imaging is a major source of ionizing radiation exposure in healthcare. Effective radiation protection relies not only on facility design but also on healthcare staff knowledge, atti…
Levart D, Wicks S, Heraghty N, Kalogianni E et al.
BackgroundThe administration of ¹⁷⁷Lu-DOTATATE peptide receptor radionuclide therapy to patients for the treatment of well-differentiated, metastatic neuroendocrine tumours poses an external radiation…
Loh J, Tan YJ, Joseph K, Sabeeha R et al.
BackgroundNuclear imaging is the cornerstone of clinical practice across many disciplines. Few innovations in imaging have addressed occupational health of radiographers exposed to radiation in their …
Pidkajetsky D, Koufi V.
The evolution of medical imaging technology has been marked by significant advancements in various modalities, leading to improved diagnostic capabilities, patient care, and treatment outcomes. One of…
Chipiga L, Likhacheva A, Vodovatov A, Zvonova I et al.
The implementation of novel therapeutic radiopharmaceuticals requires developing, updating, and harmonizing requirements for radiation safety in radiopharmaceutical therapy (RPT). Public exposure from…
Mohamadi Baghmolaei Z, Fardid R, Haghani M, Haddadi G et al.
BackgroundNuclear medicine is an integral and developing field in diagnosing and treating diseases. Monitoring individuals' protection and radiation contamination in the workplace is vital for preserv…
Gervot H, Letessier W, Loess J, Bayle-Escurat C et al.
The Nuclear Medicine Department of Sainte-Anne military hospital in Toulon uses 99mTc, 123I and 18F unsealed sources to provide therapeutic and diagnostic care. For a few years, only ambient air and s…
Kasmat NK, Mohamad NS, Tajuddin MA, Mahmud MH.
This study is aimed to determine knowledge and practices on radiation protection among radiographers in nuclear medicine department. A cross-sectional survey was conducted among radiographers in nucle…
Cao TT, Aalbersberg EA, Geluk-Jonker MM, Hendrikx JJMA.
BackgroundAutomated dispensing systems (ADSs) for radiopharmaceuticals have been developed to reduce the radiation exposure of personnel, to improve the accuracy of the dispensed dose and to limit the…
Thomson WH.
ObjectiveTo calculate depth-weighted doses for 223 Ra, 212 Pb and 225 Ac for the skin sites of trunk, arms/legs, face, wrist, back of hand, fingertip, back and side of fingers using VARSKIN+v1.2.Metho…
Mosima L, Muzamhindo N, Lundie M, Summers B.
BackgroundPositron emission tomography/computed tomography (PET/CT) is an imaging modality that combines images from high-energy gamma rays emitted by a positron emitting radiopharmaceutical and those…
Murtha N, Morrison H, Roumeliotis M, Quirk S et al.
Background¹⁷⁷ Lu prostate-specific membrane antigen (PSMA) therapy prolongs survival for some prostate cancer patients. To adopt this technique, institutions may need to evaluate the suitability of ex…
Cunha L, Baete K, Leijen C, Jamar F.
The recent development of radionuclide therapy and radioligand therapy has raised a call for achieving the highest quality standards, for either radiopharmacy or radiation protection. Novel radionucli…
Marengo M, Infantino A.
Purpose²²⁵Ac is the most promising alpha emitter for radiopharmaceutical therapy. Labeling PSMA, it showed to be effective in the treatment of prostate cancer and research is undergoing in order to im…
Tsai CJ, Chang KW, Yang BH, Wu PH et al.
Emerging molecular and precision medicine makes nuclear medicine a de facto choice of imaging, especially in the era of target-oriented medical care. Nuclear medicine is minimally invasive, four-dimen…
Barbosa N, Castillo LS, Quimbayo JS.
AbstractClinical uses of radiopharmaceuticals imply the administration of radioactive substances that are mainly excreted through urine. The Nuclear Medicine Department at the Instituto Nacional de Ca…
Elliott J, Weatherley M.
Attention to the implications of common needle stick injuries has focused heavily on the risk of cross-infection from blood-borne pathogens. An additional risk to the nuclear medicine healthcare worke…
Nyathi M.
BackgroundRadiopharmaceuticals are used for the diagnosis, treatment, staging, and follow- up of various diseases. However, there is concern that the ionizing radiation (gamma rays, α and ß particles)…
Marengo M, Martin CJ, Rubow S, Sera T et al.
Medical radiation accidents and unintended events may lead to accidental or unintended medical exposure of patients and exposure of staff or the public. Most unintended exposures in nuclear medicine w…
Dhingra J, Santana C, Harvey J, Miller A et al.
Establishing a cause-and-effect relationship for an adverse event is one of the key steps in preventing them and involves multiple people, resources, and steps, thus requiring a root cause analysis. H…
Mayes CD.
Ventilation/Perfusion scanning for suspected pulmonary embolism is undergoing a renaissance due to the advent of single-photon emission computed tomography (SPECT). The scan protocol demands the inhal…
Labbe E, Peyronnet D, Desmonts C, Vigne J.
Radioiodine therapy using oral administration of Iodine-131 (I) is a widespread employed strategy for the treatment of hyperthyroidism and thyroid cancer. Such a therapy requires well-trained staff, e…
Lopes NB, Almeida IV, Lopes PHS, Vicentini VEP.
Background Healthcare workers occupationally exposed to ¹⁸F-FDG cannot wear protective equipment, such as lead aprons, since the interaction between high energy radiation (511 keV) and metal increases…
Adliene D, Griciene B, Skovorodko K, Laurikaitiene J et al.
BackgroundReconstruction and analysis of low doses received by the occupationally exposed medical radiation workers, especially nuclear medicine staff dealing with radioisotopes may significantly cont…
Demeter S, Goertzen AL, Patterson J.
Based on ongoing research on ionizing radiation thresholds for cataracts, the International Commission on Radiological Protection has proposed new guidelines lowering the annual occupational lens of e…
Martin T, Moyon A, Fersing C, Terrier E et al.
BackgroundMany nuclear medicine departments have equipped themselves with automated dispensing systems (ADS) for PET radiopharmaceuticals, in both the operators' and the patients' interests. Whether p…
Brudecki K, Borkowska E, Gorzkiewicz K, Kostkiewicz M et al.
This paper presents the results of measurements of 99mTc activity concentrations in indoor air in a nuclear medicine department and resulting estimated 99mTc intake by medical personnel. 99mTc air act…
He X, Zhao R, Rong L, Yao K et al.
Wearing lead X-ray-protective aprons is a routine in nuclear medicine department in parts of China. However, the staff are often perplexed by questions such as if it is imperative to wear aprons when …
Zhang-Yin J, Dirand AS, Sasanelli M, Corrégé G et al.
¹²³I-metaiodobenzylguanidine (MIBG) and ¹¹¹In-pentetrotide SPECT have been used for functional imaging of neuroendocrine tumors (NETs) for the last 2 decades. More recently, PET/CT imaging with ¹⁸F-FD…
Demir M, Abuqbeitah M, Uslu-Beşli L, Yıldırım Ö et al.
The aim of this study is to investigate the outpatient treatment protocol and radiation safety of a new-emerging lutetium-177 ((177)Lu) prostate specific membrane antigen (PSMA) therapy. This work ana…
Jha AK, Singh AM, Mithun S, Shah S et al.
Positron emission tomography (PET) has been in use for a few decades but with its fusion with computed tomography (CT) in 2001, the new PET/CT integrated system has become very popular and is now a ke…
Movahedi MM, Abdi A, Mehdizadeh A, Dehghan N et al.
BackgroundLead-based shields are the standard method of intraoperative radiation protection in the radiology and nuclear medicine department. Human lead toxicity is well documented. The lead used is h…
Alzimami KS, Ma AK.
ObjectivePositron emission tomography (PET) using zirconium-89 ((89)Zr) is complicated by its complex decay scheme. In this study, we quantified the effective dose from (89)Zr and compared it with flu…
Lecchi M, Lucignani G, Maioli C, Ignelzi G et al.
PurposeIn nuclear medicine, radiopharmaceuticals are usually administered in unit doses partitioned from multi-dose vials. The partitioning typically takes place in a radiopharmacy, depending on local…
Peet DJ, Morton R, Hussein M, Alsafi K et al.
We describe the design of a fixed positron emission tomography (PET)/CT facility and the use of a simulated instantaneous dose-rate plot to visually highlight areas of potentially high radiation expos…
Ravichandran R, Binukumar JP, Sreeram R, Arunkumar LS.
Radioactive wastes from hospitals form one of the various types of urban wastes, which are managed in developed countries in a safe and organized way. In countries where growth of nuclear medicine ser…
Ruhman N, Grantham V, Martin C.
UnlabelledThis study assesses the effectiveness of using everyday cleaning agents for the radioactive decontamination of wet (99m)Tc-pertechnetate spills in the nuclear medicine department.MethodsSix …
Covens P, Berus D, Vanhavere F, Caveliers V.
Significant staff exposure is generally expected during PET-and PET/CT applications. Whole-body doses as well as extremity doses are usually higher per procedure compared with SPECT applications. Disp…
Fog LS, Collins P.
The literature contains both endorsements of, and advice against, the use of protective apparel in nuclear medicine procedures. The main issues usually centre around: Whether the shielding which can b…
Zanzonico P, Dauer L, St Germain J.
Positron emission tomography (PET) and single-photon emission computed tomography (SPECT) are well- established and indispensable imaging modalities in modern medicine. State-of-the-art computed tomog…
Hippeläinen E, Nikkinen P, Ihalainen T, Uusi-Simola J et al.
The estimation of shielding requirement of a new positron emission tomography (PET) facility is essential. Because of penetrating annihilation photons, not only radiation safety in the vicinity of pat…
Roberts FO, Gunawardana DH, Pathmaraj K, Wallace A et al.
ObjectiveThe use of PET in Australia has grown rapidly. We conducted a prospective study of the radiation exposure of technologists working in PET and evaluated the occupational radiation dose after i…
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