Sentinel lymph node-guided modification of postoperative radiotherapy in oral tongue squamous cell carcinoma: a retrospective dosimetric and NTCP modelling study.

Björgvinsson E; Kolev A; Onjukka E; Hedman M; Tedgren ÅC; Södergren L; Friesland S; Margolin G; Cardell LO; Gubanski M.

doi:10.1016/j.ctro.2026.101306

8 Oct 2026📖 Free full textPeer-ReviewedPubMedResearch ArticleDiagnosticTherapeuticClinical and translational radiation oncology · 2027

Sentinel lymph node-guided modification of postoperative radiotherapy in oral tongue squamous cell carcinoma: a retrospective dosimetric and NTCP modelling study.

Björgvinsson E, Kolev A, Onjukka E, Hedman M, Tedgren ÅC, Södergren L (+4 more)

📖 Read the full paper (free)doi:10.1016/j.ctro.2026.101306 →

Abstract

•SLNB identified lymphatic drainage beyond standard elective volumes in nearly half of OTSCC patients.•SLNB may guide individualized postoperative radiotherapy, including omission of contralateral neck irradiation in selected patients.•Adapted plans significantly reduced estimated NTCPs for xerostomia and dysphagia.•SLNB may support individualized de-escalation and optimization of elective neck irradiation in OTSCC.