Prone accelerated partial breast irradiation after breast-conserving surgery: five-year results of 100 patients.
Formenti SC, Hsu H, Fenton-Kerimian M, Roses D, Guth A, Jozsef G (+2 more)
Abstract
PurposeTo report the 5-year results of a prospective trial of three-dimensional conformal external beam radiotherapy (3D-CRT) to deliver accelerated partial breast irradiation in the prone position.Methods and materialsPostmenopausal patients with Stage I breast cancer with nonpalpable tumors ResultsOne hundred patients were enrolled in this institutional review board-approved prospective trial, one with bilateral breast cancer. One patient withdrew consent after simulation, and another patient elected to interrupt radiotherapy after receiving two treatments. Ninety-eight patients were evaluable for toxicity, and, in 1 case, both breasts were treated with partial breast irradiation. Median patient age was 68 years (range, 53-88 years); in 55% of patients the tumor size was ConclusionsFive-year efficacy and toxicity of 3D-CRT delivered in prone partial breast irradiation are comparable to other experiences with similar follow-up.