Heart dose reduction by prone deep inspiration breath hold in left-sided breast irradiation.
Mulliez T, Veldeman L, Speleers B, Mahjoubi K, Remouchamps V, Van Greveling A (+5 more)
Abstract
Background and purposeCardiac disease has been related to heart dose after left-sided breast radiotherapy. This trial evaluates the heart sparing ability and feasibility of deep inspiration breath hold (DIBH) in the prone position for left-sided whole breast irradiation (WBI).Materials and methodsTwelve patients underwent CT-simulation in supine shallow breathing (SB), supine DIBH, prone SB and prone DIBH. A validation cohort of 38 patients received prone SB and prone DIBH CT-scans; the last 30 patients were accepted for prone DIBH treatment. WBI was planned with a prescription dose of 40.05 Gy.ResultsDIBH was able to reduce (pConclusionsThis trial demonstrates the ability and feasibility of prone DIBH to acquire optimal heart and lung sparing for left-sided WBI.