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Therapeutic📖 Free full textPeer-ReviewedPubMedJournal of applied clinical medical physics · 2026

Maskless head and neck radiotherapy using surface-guided radiation therapy: initial clinical feasibility of real-time setup, intrafraction monitoring, and automatic beam-hold.

Robinson A, Kandula S.

BackgroundThermoplastic immobilization remains standard for head and neck radiation therapy, but rigid face masks may produce clinically meaningful anxiety, claustrophobia, and treatment intolerance i…

QA & dosimetry📖 Free full textPeer-ReviewedPubMedTechnical innovations & patient support in radiation oncology · 2026

Correction of image-guided radiotherapy and intrafraction motion using ExacTrac dynamic for head and neck cancer patients.

Holst SDI, Andersen M, Jakobsen AR, Nielsen MS.

Daily cone-beam computed tomography (CBCT) based image-guided radiotherapy (IGRT) with six degrees of freedom (6DOF) is standard for head and neck cancer. We retrospectively analyzed 669 sessions from…

QA & dosimetryPeer-ReviewedPubMedStrahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2026

Effects of intrafractional motion on targeting accuracy in frameless single-isocenter multi-target stereotactic radiosurgery.

Grohmann M, Petersen C, Hintelmann K, Todorovic M.

PurposeThis study evaluates the impact of intrafractional motion on targeting accuracy in frameless single-isocenter multi-target stereotactic radiosurgery (SIMT) for brain metastases and examines the…

QA & dosimetry📖 Free full textPeer-ReviewedPubMedJournal of medical physics · 2026

Clinical Implementation and Accuracy Evaluation of a Novel Intrafraction Cone-beam Computed Tomography Technique for Stereotactic Radiosurgery and Radiotherapy.

Jaiswal D, Goyal M, Bhatt CP.

PurposeTo evaluate the clinical implementation and setup accuracy of real-time intrafraction cone-beam computed tomography imaging during stereotactic radiosurgery and stereotactic radiotherapy.Materi…

QA & dosimetry📖 Free full textCited 1×Peer-ReviewedPubMedBMC cancer · 2026

Comparison of six-degree-of-freedom registration errors across different anatomical registration regions in head and neck radiotherapy under identical CBCT conditions.

Lin W, Xiao L, Chen J, Lin X et al.

OBJECTIVE: Cone-beam computed tomography (CBCT) has been widely adopted for patient setup evaluation and error correction in head and neck radiotherapy. Although different anatomical registration regi…

Therapeutic📖 Free full textPeer-ReviewedPubMedReports of practical oncology and radiotherapy · 2025

Setup errors during curative radiation therapy in intracranial neoplasms - is a 5 MM PTV margin an overestimation?

Veluthattil AC, Natarajan N, Thiruthiyil A.

BackgroundThe aim of the study was to determine an ideal planning target volume (PTV) margin using the Van Herks formula by auditing and reporting the setup errors in 6 dimensions of patients undergoi…

QA & dosimetry📖 Free full textPeer-ReviewedPubMedIn vivo (Athens, Greece) · 2025

Validation of Catalyst<sup>+</sup> HD System Under Varying Postural, Couch Angle, and Isocenter Conditions in Intracranial Stereotactic Irradiation.

Suzuki T, Ohira S, Imanishi Y, Yamaguchi Y et al.

Background/aimThis study assessed the positional detection accuracy of the Catalyst+ HD system for intracranial stereotactic irradiation (STI) under clinically relevant conditions, including variation…

Therapeutic📖 Free full textCited 1×Peer-ReviewedPubMedFrontiers in oncology · 2025

Analysis of the impact of rotation error on PTV margins in multiple brain metastases fractionated stereotactic radiotherapy based on single-isocenter multi-target technique.

Li Y, Hua R, Dai L, Chen W et al.

BackgroundRotational error cannot be overlooked in single-isocenter multi-target (SIMT) stereotactic radiotherapy. This retrospective study aimed to evaluate the treatment accuracy of linear accelerat…

Therapeutic📖 Free full textPeer-ReviewedPubMedTechnical innovations & patient support in radiation oncology · 2024

A prospective randomized study comparing two frameless immobilization systems for cranial stereotactic radiotherapy.

Callens D, Benazzouz C, Stessens L, Piot W et al.

IntroductionThe Dual Shell Encompass Fibreplast™ System (DS-Encompass) by CQ Medical™ is validated for frameless immobilization in stereotactic brain radiotherapy. An alternative mask model has been p…

TherapeuticQA & dosimetry📖 Free full textCited 3×Peer-ReviewedPubMedJournal of applied clinical medical physics · 2024

Dosimetric effects of rotational errors for single isocenter multiple targets in HyperArc plans: A phantom and retrospective imaging analysis study.

Golmakani S, McGrath AN, Williams TJ.

PurposeThis study uses a phantom to investigate the dosimetric impact of rotational setup errors for Single Isocenter Multiple Targets (SIMT) HyperArc plans. Additionally, it evaluates intra-fractiona…

Therapeutic📖 Free full textCited 2×Peer-ReviewedPubMedJournal of applied clinical medical physics · 2023

Mask dependency of the lacrimal gland dose under whole brain radiotherapy when the six-degrees of freedom couch is not available.

Yoon JW, Kim MY, Park S, Cheong KH et al.

BackgroundDry eye syndrome has been recently reported in patients who underwent whole brain radiotherapy (WBRT). WBRT based on a couch with three-degrees of freedom (3D) can occasionally be performed …

QA & dosimetry📖 Free full textCited 36×Peer-ReviewedPubMedJournal of applied clinical medical physics · 2021

Accuracy of surface-guided patient setup for conventional radiotherapy of brain and nasopharynx cancer.

Lee SK, Huang S, Zhang L, Ballangrud AM et al.

PurposeTo evaluate the accuracy of surface-guided radiotherapy (SGRT) in cranial patient setup by direct comparison between optical surface imaging (OSI) and cone-beam computed tomography (CBCT), befo…

QA & dosimetry📖 Free full textCited 24×Peer-ReviewedPubMedJournal of applied clinical medical physics · 2021

Intra-fractional patient motion when using the Qfix Encompass immobilization system during HyperArc treatment of patients with brain metastases.

Komiyama R, Ohira S, Ueda H, Kanayama N et al.

PurposeThis study investigated the intra-fractional motion (IM) of patients immobilized using the QFix Encompass Immobilization System during HyperArc (HA) treatment.MethodHA treatment was performed o…

QA & dosimetry📖 Free full textCited 36×Peer-ReviewedPubMedJournal of applied clinical medical physics · 2020

Effect of setup error in the single-isocenter technique on stereotactic radiosurgery for multiple brain metastases.

Nakano H, Tanabe S, Utsunomiya S, Yamada T et al.

In conventional stereotactic radiosurgery (SRS), treatment of multiple brain metastases using multiple isocenters is time-consuming resulting in long dose delivery times for patients. A single-isocent…

QA & dosimetry📖 Free full textCited 25×Peer-ReviewedPubMedJournal of applied clinical medical physics · 2020

The potential of an optical surface tracking system in non-coplanar single isocenter treatments of multiple brain metastases.

Swinnen ACC, Öllers MC, Loon Ong C, Verhaegen F.

To evaluate the accuracy of a commercial optical surface tracking (OST) system and to demonstrate how it can be implemented to monitor patient positioning during non-coplanar single isocenter stereota…

QA & dosimetry📖 Free full textCited 25×Peer-ReviewedPubMedRadiation oncology (London, England) · 2019

Intrafractional 6D head movement increases with time of mask fixation during stereotactic intracranial RT-sessions.

Mangesius J, Seppi T, Weigel R, Arnold CR et al.

BackgroundThe present study investigates the intrafractional accuracy of a frameless thermoplastic mask used for head immobilization during stereotactic radiotherapy. Non-invasive masks cannot complet…

QA & dosimetry📖 Free full textCited 34×Peer-ReviewedPubMedJournal of applied clinical medical physics · 2018

Monitoring frequency of intra-fraction patient motion using the ExacTrac system for LINAC-based SRS treatments.

Lewis BC, Snyder WJ, Kim S, Kim T.

PurposeThe aim of this study was to investigate the intra-fractional patient motion using the ExacTrac system in LINAC-based stereotactic radiosurgery (SRS).MethodA retrospective analysis of 104 SRS p…

QA & dosimetry📖 Free full textCited 36×Peer-ReviewedPubMedJournal of applied clinical medical physics · 2016

Improved setup and positioning accuracy using a three-point customized cushion/mask/bite-block immobilization system for stereotactic reirradiation of head and neck cancer.

Wang H, Wang C, Tung S, Dimmitt AW et al.

The purpose of this study was to investigate the setup and positioning uncertainty of a custom cushion/mask/bite-block (CMB) immobilization system and determine PTV margin for image-guided head and ne…

QA & dosimetry📖 Free full textCited 32×Peer-ReviewedPubMedJournal of applied clinical medical physics · 2015

Clinical experience with two frameless stereotactic radiosurgery (fSRS) systems using optical surface imaging for motion monitoring.

Li G, Ballangrud A, Chan M, Ma R et al.

The purpose of this study was to compare two clinical immobilization systems for intracranial frameless stereotactic radiosurgery (fSRS) under the same clinical procedure using cone-beam computed tomo…

QA & dosimetry📖 Free full textCited 42×Peer-ReviewedPubMedJournal of applied clinical medical physics · 2012

Six degrees of freedom CBCT-based positioning for intracranial targets treated with frameless stereotactic radiosurgery.

Dhabaan A, Schreibmann E, Siddiqi A, Elder E et al.

Frameless radiosurgery is an attractive alternative to the framed procedure if it can be performed with comparable precision in a reasonable time frame. Here, we present a positioning approach for fra…

QA & dosimetry📖 Free full textCited 65×Peer-ReviewedPubMedRadiation oncology (London, England) · 2012

Dosimetric consequences of translational and rotational errors in frame-less image-guided radiosurgery.

Guckenberger M, Roesch J, Baier K, Sweeney RA et al.

BackgroundTo investigate geometric and dosimetric accuracy of frame-less image-guided radiosurgery (IG-RS) for brain metastases.Methods and materialsSingle fraction IG-RS was practiced in 72 patients …

QA & dosimetryCited 37×Peer-ReviewedPubMedRadiotherapy and oncology · 2012

Clinical comparison of positional accuracy and stability between dedicated versus conventional masks for immobilization in cranial stereotactic radiotherapy using 6-degree-of-freedom image guidance system-integrated platform.

Ohtakara K, Hayashi S, Tanaka H, Hoshi H et al.

PurposeTo compare the positioning accuracy and stability of two distinct noninvasive immobilization devices, a dedicated (D-) and conventional (C-) mask, and to evaluate the applicability of a 6-degre…

QA & dosimetryTherapeuticCited 92×Peer-ReviewedPubMedInternational journal of radiation oncology, biology, physics · 2012

Clinical evaluation of a robotic 6-degree of freedom treatment couch for frameless radiosurgery.

Gevaert T, Verellen D, Engels B, Depuydt T et al.

PurposeTo evaluate the added value of 6-degree of freedom (DOF) patient positioning with a robotic couch compared with 4DOF positioning for intracranial lesions and to estimate the immobilization char…

QA & dosimetryCited 63×Peer-ReviewedPubMedInternational journal of radiation oncology, biology, physics · 2008

Cone beam CT image guidance for intracranial stereotactic treatments: comparison with a frame guided set-up.

Masi L, Casamassima F, Polli C, Menichelli C et al.

PurposeAn analysis is performed of the setup errors measured by a kV cone beam computed tomography (CBCT) for intracranial stereotactic radiotherapy (SRT) patients immobilized by a thermoplastic mask …