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📖 Free full textPeer-ReviewedPubMedPhysics in medicine and biology · 2026

A real-time image-guided six-degree-of-freedom internal-external correlation framework for motion monitoring on a standard linear accelerator.

Kaczynska A, Jin F, Stewart M, Kipritidis J et al.

Objective.Real-time six-degree-of-freedom (6DoF) tumour motion monitoring is important for accurate stereotactic body radiotherapy (SBRT) of thoracic and abdominal cancer sites, yet existing approaches either require specialised imaging hardware or continuous fluoroscopic imaging. This study presents the development and first experimental implementation of a real-time image-gui…

📖 Free full textPeer-ReviewedOpenAlexPubMed · 2026

AI-Driven Workflow for Automated Colorimetric Isothermal Amplification for Robust Pathogen Detection on Portable Devices.

Ke Xu, Matthew L. Cavuto, Kenny Malpartida-Cardenas, Marcus Pond et al.

Point-of-Care (POC) portable devices have shown significant potential for rapid pathogen identification in limited-resource settings. Colorimetric LAMP (cLAMP)-based POC nucleic acid testing is particularly promising due to its speed, sensitivity, and simple visual readout. However, there is a need for a universal, automated color detection method to improve ease of use and red…

Peer-ReviewedPubMedThe British journal of radiology · 2026

Determination of institute specific CTV to PTV prostate margins using the 2020 BIR IGRT geometric uncertainty guidelines for a conventional linear accelerator.

Moran M, Jamaluddin MF, Lyons CA, O'Cathail SM et al.

ObjectivesA multitude of differing clinical practice exists for prostate radiotherapy, this includes dose prescription, planning methods, asymmetric margins and the presence, or not, of fiducial markers. Institute specific CTV to PTV margins expansion is desirable for optimum treatment of patients. Margins can be determined by assessing geometric errors inherent in radiotherapy…

Peer-ReviewedPubMedBiomedical physics & engineering express · 2026

Quantifying daily residual motion of bilateral diaphragmatic domes using an iterative detection algorithm for breath-hold radiation therapy.

Wei J, Chao M, Narang A, Mao W.

Breath-hold (BH) techniques reduce respiratory motion and planning margins in thoracic and abdominal radiotherapy, but residual motion during BH can still compromise targeting accuracy. Direct tumor tracking remains technically challenging for many abdominal sites; tracking the diaphragm, which may correlate with implanted fiducial markers, could provide a practical surrogate. …

Peer-ReviewedPubMedInternational journal of computer assisted radiology and surgery · 2026

Implementation of monocular near-infrared camera tracking in MRI and CT navigation systems.

Moviglia J, Kuntz L, Kehrein F, Herrmann UF et al.

Image-guided intervention (IGI) systems support anatomical registration and real-time instrument tracking during minimally invasive procedures. Existing robotic and navigation solutions are often single-modality, costly, or have limited MRI compatibility. This study presents a cost-effective monocular near-infrared (NIR) tracking system for IGI across multiple modalities while …

Peer-ReviewedPubMedThe British journal of radiology · 2026

Dosimetric robustness of tumour- and fiducial-based tracking in Radixact lung stereotactic body radiotherapy: a four-dimensional CT-based simulation using imaging-derived tracking-error scenarios.

Ebinuma Y, Inoue T, Shirata R, Takatsu J et al.

ObjectivesTo compare the dosimetry and robustness of two Radixact Synchrony lung stereotactic body radiotherapy (SBRT) tracking strategies: tumour-based lung tracking with respiratory modelling (LwR) and fiducial-based tracking with respiratory modelling (FwR).MethodsTen stage I non-small-cell lung cancer patients were retrospectively analysed. SBRT plans (42 Gy in 4 fractions)…

Peer-ReviewedPubMedPhysics in medicine and biology · 2026

CBCT-based synthetic MRI generation for target localization during deep inspiration breath hold (DIBH) abdominal radiotherapy.

Quintero P, Yu V, Wu C, Smith L et al.

Introduction.This study aims to generate synthetic-magnetic resonance imaging (synMRI) for abdominal patients undergoing radiotherapy using deep inspiration breath hold (DIBH) on a conventional Linac.Methods.Extended cardiac-torso (XCAT) phantom and patient data were used to develop and test a patient-specific model to generatesynMRI. During patient simulation, 6 DIBH-MRIs and …

Peer-ReviewedPubMedInternational journal of radiation oncology, biology, physics · 2026

Liver tumor motion and reconstructed doses in a clinical trial of respiratory gated proton therapy for hepatocellular carcinoma.

Nankali S, Worm ES, Thomsen JB, Stick LB et al.

PurposePencil beam scanning proton therapy of hepatocellular carcinoma (HCC) may reduce the risk of radiation-induced liver disease compared to photon radiotherapy, but tumor motion and anatomical changes can distort the dose. This was investigated through daily reconstruction of the delivered dose in a clinical trial of gated HCC proton therapy.Methods and materialsSixteen pat…