Knowledge Hub · CRP™ Dispensing System
The automation inside the cell —not the cell itself.
CRP isn\'t a shielded hot cell. It\'s the dispensing automation that drops into one — typically the FLEX in our setup. This page explains, in plain language, what CRP does (precise F-18 vial dispensing, hands-out-of-cell), what it leaves to the host cell (shielding, Grade A environment, AERB licensing), and why the SYNT → FLEX + CRP stack is the Saxsons-supplied package for a modern Indian cyclotron radiopharmacy.
Where CRP sits
From the cyclotron to the patient — CRP is inside the FLEX
Step 1
Cyclotron
Particle accelerator makes the F-18
Step 2
SYNT
Automated chemistry turns it into FDG (or another PET tracer)
Step 3
FLEX + CRP
FLEX is the Grade A cell; CRP is the automation inside it
Step 4
Patient
Syringe leaves the cell, scanned within hours
Why this matters
Six things CRP delivers, explained simply
It's a module, not a hot cell
The automation that goes inside the shielded cell
Most things called "dispensing systems" come with their own shielded box. CRP is the opposite — it's the dispensing automation engineered to drop into a shielded hot cell you already have (or are buying alongside, like the FLEX). The host cell provides the shielding and the GMP environment; CRP brings the precision and the hands-out-of-cell workflow.
Based on: CRP product page — "compact dimensions, can be installed in any type of shielded laminar flow cell"
Read source ↗Better than 1% precision
Volume deviation guaranteed under 1%
Patient dose accuracy starts with how precisely the volume is dispensed. (the manufacturer )guarantees CRP volume / weight deviation stays under 1% of target. That's the precision floor a modern radiopharmacy expects from an automated unit-dose bench.
Based on: CRP product page — "deviation from the target volume (weight) guaranteed to be less than 1%"
Read source ↗Open and closed vials
Both vial workflows in one module
CRP Compact dispenses open vials (with rubber stopper + crimped aluminum-ring cap) and adds closed-vial via septum piercing as an option. CRP Compact plus does open-vial dispensing with either crimped or push-fit capping. The same module handles the F-18 unit-dose workflow shapes you'll meet day-to-day.
Based on: CRP product page — Compact and Compact plus variant descriptions
Read source ↗Annex 1 compliant
Designed for sterile-conditions dispensing
The European pharmaceutical rules require unit-dose dispensing of sterile injectables to happen under aseptic conditions. CRP is positioned by (the manufacturer )as compliant with EU GMP Annex 1, the sterile-medicines rulebook (revised 2022). The host cell provides the Grade A environment; CRP runs the dispensing process inside it.
Based on: CRP product page — "compliant with EU GMP Annex 1 regulations"
Read source ↗100 units worldwide
Not a first-of-its-kind risk
(the manufacturer )publishes a 100-units-installed install base for CRP. For an Indian cyclotron site evaluating dispensing automation, that's a meaningful reference base — the device exists, it ships, it works in clinical practice.
Based on: CRP product page — "100 CRP installed around the world"
Read source ↗Pairs with FLEX
One manufacturer-supplied stack: SYNT → FLEX + CRP → patient
SYNT is where the chemistry happens; FLEX is the Grade A shielded cell where unit doses are drawn; CRP is the automation inside FLEX that actually does the dispensing. Buying all three as a the manufacturer stack means one calibration chain, one teleassistance contract, and one consistent audit trail across the cyclotron radiopharmacy.
Based on: SYNT + FLEX + CRP product pages
Read source ↗CRP at a glance
< 1%
Volume deviation
(the manufacturer )guaranteed precision
100+
Units worldwide
manufacturer-published install base
Annex 1
EU GMP framework
Sterile-conditions compliant
F-18
India primary use
FDG unit-dose dispensing
Scope of this page
CRP is a dispensing module, not a hot cell. Lead shielding, Grade A environment and AERB licensing all sit with the host cell (typically theFLEXin a Saxsons-supplied Indian setup). The F-18 primary-use focus is Saxsons-supplied market reality — the CRP public page uses generic "radiopharmaceutical" language and does not name specific isotopes. The "compliant with EU GMP Annex 1" claim is Tema\'s marketing language; CRP is the automation that supports an Annex 1 workflow, but certification of the radiopharmacy programme is the operator\'s responsibility.
Manufacturer references + sibling product
CRP product page, brochure PDF, and the FLEX hot cell CRP typically lives inside for an Indian cyclotron radiopharmacy.
CRP — Manufacturer product page
Manufacturer page with the CRP Compact / Compact plus specification and Vimeo product demos.
CRP Compact — Manufacturer brochure (PDF)
CRP Compact / CRP Compact plus product brochure (2024 edition).
FLEX — sibling dispensing hot cell
The Grade A shielded cell CRP typically lives inside for an Indian cyclotron radiopharmacy.
Where next
Three more pages, depending on what you need.
Product page →
CRP specs and demos
Compact vs Compact plus, vial-type matrix, brochure, two the manufacturer Vimeo product demos.
Host cell →
FLEX dispensing hot cell
The Grade A shielded hot cell CRP typically lives inside — 100 mm Pb India config.
For the radiopharmacist →
Automation scope
What CRP automates and what stays manual — for the QA / radiopharmacist team.