Radio-guided & fluorescence-guided surgery — latest research
Sentinel-lymph-node biopsy, ROLL and radio-guided surgery — gamma-probe, ICG near-infrared fluorescence and hybrid ICG-⁹⁹ᵐTc tracer evidence across breast, melanoma, gynaecological, urological and head-and-neck oncology. Curated daily from Europe PMC (PubMed + PMC + preprints) and OpenAlex — free-full-text link on each open-access paper.
Aramis Raiola, Fabio Acerbi, Cyril Martin Alispach, Domenico della Volpe et al.
Abstract Background The POSiCS camera is a handheld and wireless, small field-of-view gamma camera developed for use in radio-guided surgery (RGS), with sentinel lymph node biopsy (SLNB) as its benchm…
Jansson M, Bark R, Elliot A, Hammarstedt-Nordenvall L et al.
Background Salivary gland carcinomas are rare and heterogeneous malignancies, more common in the parotid gland but also in submandibular and minor salivary glands. Surgery, often combined with radioth…
Denardi D, Oliveira-Junior I, Ferigatto JL, Buexm LA et al.
Sentinel Lymph Node (SLN) mapping is a highly accurate method for assessing axillary status in breast cancer, using various tracers such as Patent Blue, Technetium-99 m, Indocyanine Green, and Superpa…
Background Sentinel lymph node (SLN) biopsy often combines technetium-99m (99mTc), indocyanine green (ICG), and methylene blue (MB), but few contemporary audits quantify the performance of each tracer…
Background/Objectives : Sentinel lymph node biopsy (SLNB) is currently the standard approach for axillary staging in breast cancer. Conventional techniques are radioisotope-based (Technetium-99m, Tc99…
Darai A, de Gooyer JM, Ubels S, Bremers AJA et al.
Background Selection of suitable candidates for intraoperative tumour detection and cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) is important for improvi…
Background/Objectives : Cervical cancer primarily disseminates through the lymphatic system, with the metastatic involvement of pelvic and para-aortic lymph nodes significantly impacting prognosis and…
Donders DNV, Mahieu R, Tellman RS, Philippens MEP et al.
Objectives: To assess the efficacy of magnetic resonance (MR) lymphography with gadobutrol contrast for sentinel lymph node (SLN) mapping in early-stage oral squamous cell carcinoma (OSCC). Methods: T…
Introduction High-risk neuroblastoma, particularly in the relapse/refractory (R/R) setting, poses unique challenges to obtaining the representative-quality tissue that is mostly required for molecular…
Cabıoğlu N, Karanlık H, Yılmaz R, Emiroğlu S et al.
Background Any advantage of performing targeted axillary dissection (TAD) compared to sentinel lymph node (SLN) biopsy ( SLNB) is under debate in clinically node-positive (cN+) patients diagnosed with…
Background Sentinel lymph node biopsy (SLNB) is used to improve the staging of and guide treatment in patients with early-stage T1-T2 N0 oral squamous cell carcinoma (OSCC). The role of sentinel nodes…
Frederiks CN, Overwater A, Bergman JJGHM, Pouw RE et al.
Background Selective lymphadenectomy using sentinel node-navigated surgery (SNNS) might offer a less invasive alternative to esophagectomy in patients with high-risk T1 esophageal adenocarcinoma (EAC)…
Jeremiasse B, van Scheltinga CEJT, Smeele LE, Tolboom N et al.
Background Standard sentinel lymph node procedure (SNP) in pediatric cancer consists of a preoperative injection with 99m technetium nanocolloid in combination with an optional intraoperative injectio…
Rietbergen DDD, van Gennep EJ, KleinJan GH, Donswijk M et al.
Rationale In muscle-invasive bladder cancer (MIBC), lymph node invasion has proven to be an independent predictor of disease recurrence and cancer-specific survival. We evaluated the feasibility of ta…
de Gooyer JM, Elekonawo FMK, Bremers AJA, Boerman OC et al.
In patients with colorectal peritoneal metastases scheduled for cytoreductive surgery, accurate preoperative estimation of tumor burden and subsequent intraoperative detection of all tumor deposits re…
Overwater A, Weusten BLAM, Ruurda JP, van Hillegersberg R et al.
Background Minimally invasive esophagectomy with two-field lymphadenectomy is standard of care for T1b esophageal adenocarcinoma (EAC) with a high risk of lymph node metastasis. Sentinel node navigati…
KleinJan GH, van Werkhoven E, van den Berg NS, Karakullukcu MB et al.
Purpose Hybrid image-guided surgery technologies such as combined radio- and fluorescence-guidance are increasingly gaining interest, but their added value still needs to be proven. In order to evalua…
Hekman MC, Rijpkema M, Muselaers CH, Oosterwijk E et al.
Intraoperative imaging with antibodies labeled with both a radionuclide for initial guidance and a near-infrared dye for adequate tumor delineation may overcome the main limitation of fluorescence ima…
den Toom IJ, van Schie A, van Weert S, Karagozoglu KH et al.
Purpose To assess the role of single-photon emission computed tomography with computed tomography (SPECT-CT) for the identification of sentinel lymph nodes (SLNs) in patients with early stage (T1-T2) …
Hassanzadeh M, Hosseini Farahabadi E, Yousefi Z, Kadkhodayan S et al.
Background Experience on sentinel node mapping in ovarian tumors is very limited. We evaluated the sentinel node concept in ovarian tumors using intra-operativeTc-99m-Phytate injection and lymphoscint…
KleinJan GH, van den Berg NS, de Jong J, Wit EM et al.
Purpose Radical prostatectomy and complementary extended pelvic lymph node dissection (ePLND) of sentinel lymph nodes (SNs) and non-sentinel lymph nodes (LNs) at risk of containing metastases are incr…
Meinhardt W, van der Poel HG, Valdés Olmos RA, Bex A et al.
Objective. To assess the relevance of sentinel lymph nodes (SNs) outside the extended pelvic lymph node dissection area (e-PLND). Patients and Methods. Evaluation of our laparoscopic SN procedures for…
Sentinel node biopsy can decrease the morbidity of breast cancer treatment significantly by sparing many patients of axillary lymph node dissection and resulting arm lymphedema. Despite widespread use…
Aim This prospective randomized clinical study was conducted to compare radioguided occult lesion localization (ROLL) with wire-guided localization to evaluate optimum localization techniques for non-…
Vermeeren L, Meinhardt W, van der Poel HG, Valdés Olmos RA.
Purpose The goal of this study was to establish the feasibility of sentinel node biopsy in patients with recurrent prostate cancer after initial local treatment and to compare lymphatic drainage patte…
Schreuder HW, Zweemer RP, van Baal WM, van de Lande J et al.
We analysed the introduction of the robot-assisted laparoscopic radical hysterectomy in patients with early-stage cervical cancer with respect to patient benefits and surgeon-related aspects of a surg…
van Esser S, Hobbelink M, Van Isselt JW, Mali WP et al.
Purpose To compare the identification rate of the sentinel node in a 1-day protocol versus a 2-day protocol in patients with a nonpalpable breast carcinoma. Methods In the 1-day protocol an average do…
van Esser S, Hobbelink MG, Peeters PH, Buskens E et al.
Background With the increasing number of non palpable breast carcinomas, the need of a good and reliable localization method increases. Currently the wire guided localization (WGL) is the standard of …
Madsen E, Gobardhan P, Bongers V, Albregts M et al.
Background Since the introduction of the sentinel lymph node (SLN) biopsy in breast cancer patients there is a renewed interest in lymphatic drainage to the internal mammary (IM) chain nodes. We evalu…
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