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Therapeutic📖 Free full textPeer-ReviewedPubMedJournal of applied clinical medical physics · 2026

Maskless head and neck radiotherapy using surface-guided radiation therapy: initial clinical feasibility of real-time setup, intrafraction monitoring, and automatic beam-hold.

Robinson A, Kandula S.

BackgroundThermoplastic immobilization remains standard for head and neck radiation therapy, but rigid face masks may produce clinically meaningful anxiety, claustrophobia, and treatment intolerance i…

TherapeuticQA & dosimetry📖 Free full textPeer-ReviewedPubMedInternational journal of radiation oncology, biology, physics · 2026

Upright Immobilization for Proton Therapy: A Critical Review and Single-Institution Experience.

Aissi S, O'Reilly S, Harari C, Morris B et al.

Upright positioning coupled with gantry-less proton therapy designs may reduce facility footprint and cost while introducing specific technical requirements for reproducible positioning, immobilizatio…

QA & dosimetry📖 Free full textPeer-ReviewedPubMedJournal of applied clinical medical physics · 2026

Evaluation of the environ SRS immobilization mask system for HyperArc: Dosimetric attenuation, dose calculation accuracy, and clinical setup reproducibility.

Robinson A, Caldwell MR.

BackgroundFrameless thermoplastic masks are standard for intracranial stereotactic radiosurgery (SRS), with the Encompass (CQ Medical) widely used on the Varian HyperArc platform. A candidate mask mus…

Therapeutic📖 Free full textPeer-ReviewedOpenAlexJournal of Neurosurgery Case Lessons · 2026

Hybrid frame-mask fixation for Gamma Knife radiosurgery of an extracranial vagal schwannoma: illustrative case

Victor Goulenko, Sarthak Sinha, Venkatesh Shankar Madhugiri, Neil D. Almeida et al.

BACKGROUND: Stereotactic radiosurgery requires high precision and stable target immobilization, especially for extracranial lesions prone to motion. Lesions located low in the neck pose unique challen…

QA & dosimetryPeer-ReviewedPubMedClinical oncology (Royal College of Radiologists (Great Britain)) · 2026

UK Photon Radiotherapy Practice for Oligodendroglioma -Data From the Analysis of Proton vs Photon Radiotherapy in Oligodendroglioma and Assessment of Cognitive Health Trial (ISRCTN:1339049) Radiotherapy Quality Assurance (RTQA) Programme.

Golten J, Bruce A, Egleston D, Miles E et al.

AimsThe APPROACH (Analysis of Proton vs Photon Radiotherapy in Oligodendroglioma and Assessment of Cognitive Health) trial is a UK randomised controlled study comparing photon radiotherapy (RT) with p…

Therapeutic📖 Free full textPeer-ReviewedPubMedRadiation oncology (London, England) · 2026

Hypofractionated stereotactic radiation therapy for optic nerve sheath meningiomas: A single-center experience and preliminary results.

Yang Y, Luo F, Wang C, Ren G et al.

BackgroundPrimary optic nerve sheath meningioma (pONSM) causes progressive vision loss. Surgery carries high morbidity (~ 94% visual impairment), and conventional fractionated radiotherapy (CFRT; 50.4…

QA & dosimetryPeer-ReviewedPubMedThe British journal of radiology · 2026

Evaluation of patient setup accuracy using optical surface guidance in postoperative radiotherapy for patients with breast cancer after breast-conserving surgery.

Wan B, Han J, Zheng Y, Liu C et al.

ObjectivesTo evaluate the clinical application of AlignRT surface-guided radiotherapy (SGRT) by quantifying interfractional setup errors in patients with breast-conserving surgery (BCS) stratified by …

QA & dosimetryTherapeuticPeer-ReviewedPubMedPractical radiation oncology · 2026

Effect of Thermoplastic Mask Cut-out on Radiation Dermatitis in Radiation Therapy for Early-Stage Glottic Cancer: Basic Assessment and Clinical Outcomes.

Suzuki K, Hiraoka S, Nakashima R, Sasaki M et al.

PurposeRadiation dermatitis is among the most common adverse events associated with radiation therapy for early-stage glottic cancer. This study evaluated the effect of cutting out a portion of the th…

QA & dosimetry📖 Free full textPeer-ReviewedPubMedJournal of applied clinical medical physics · 2026

To shift or not to shift: identifying and correcting patient motion after couch rotations in non-coplanar intracranial radiosurgery with stereoscopic X-ray imaging.

Da Silva Mendes V, Garny S, Huang L, Schönecker S et al.

BackgroundFrameless linear accelerator (linac)-based image-guided stereotactic radiosurgery (SRS) or fractionated stereotactic radiotherapy (FSRT) are a widely used treatment option for intracranial l…

QA & dosimetryPeer-ReviewedPubMedRadiological physics and technology · 2026

Evaluation of planning target margins in head and neck cancer patients undergoing radiotherapy: a multicentric study in Bangladesh.

Islam J, Kausar A, Shemanto MU, Abbas A et al.

In radiation therapy, the planning target volume (PTV) is a geometrical concept used to account for the variations of target position during treatment in terms of systematic (Σ) and random (σ) errors.…

QA & dosimetry📖 Free full textCited 1×Peer-ReviewedPubMedFrontiers in oncology · 2026

Research on real-time detection of radiotherapy setup errors and intelligent quality control methods based on artificial intelligence and big data.

Lin W, Xiao C, Xiao L, Fang J et al.

ObjectiveThis study aimed to develop and validate an unsupervised machine learning-based approach for near-real-time alerting of statistically abnormal six-dimensional (6D) radiotherapy setup errors. …

QA & dosimetry📖 Free full textPeer-ReviewedPubMedTechnical innovations & patient support in radiation oncology · 2026

Accuracy and workflow efficiency of surface-guided open-face vs. closed-face masks in SRT/SRS for brain metastases.

Obena S, Alves K, Zwahlen DR, Clivio A et al.

BackgroundOpen-face masks (OFMs) provide comparable immobilization or superior accuracy with greater patient comfort than closed-face masks (CFMs), but their impact on workflow efficiency in stereotac…

QA & dosimetry📖 Free full textPeer-ReviewedPubMedTechnology in cancer research & treatment · 2026

Impact of Voxel Grid Size and Statistical Uncertainty on Surface Depth Dose Via Various Planning Techniques and Immobilization Devices Using Monte Carlo Algorithm.

Challapalli S, Choudhary A, Nagesh J, C S et al.

IntroductionThis study aims to analyze the impact of the surface dose at depth (1-5mm) in different planning techniques and immobilization devices by varying the dose-voxel size (DVS) and statistical …

Therapeutic📖 Free full textCited 1×Peer-ReviewedPubMedPsycho-oncology · 2025

Development and Validation of a Rapid Screening Measure for Mask Anxiety in Head and Neck Cancer Patients Undergoing Radiotherapy.

Pelland MÈ, Lagadec-Gaulin L, Bahig H, Filion E et al.

ObjectiveThis study aims to develop a brief screening questionnaire for early identification of radiotherapy mask-related anxiety in patients with head and neck cancer.MethodsA cross-sectional study r…

Therapeutic📖 Free full textCited 1×Peer-ReviewedPubMedTechnical innovations & patient support in radiation oncology · 2025

Assessment of upright immobilization methods for abdominal and head-and-neck cancer treatments in a carbon ion radiotherapy setting.

Varnava M, Kawashima M, Matsumura A, Oohashi Y et al.

Background and purposeUpright patient positioning is an emerging approach in radiotherapy that may overcome current limitations in carbon ion radiotherapy (CIRT). This study evaluated upright immobili…

Therapeutic📖 Free full textCited 1×Peer-ReviewedPubMedJournal of applied clinical medical physics · 2025

Analysis of the application of 3D-printed personalized positioning fixation in nasopharyngeal carcinoma radiotherapy.

Ding Z, Li GQ, Liu Q, Zhu X et al.

ObjectiveThis study aims to evaluate the impact of personalized 3D-printed headrest devices on setup errors and dosimetry in nasopharyngeal carcinoma radiotherapy.MethodsA total of 50 nasopharyngeal c…

QA & dosimetry📖 Free full textPeer-ReviewedPubMedInternational journal of radiation oncology, biology, physics · 2026

Performance of a Novel Frameless and Maskless Robotic Head Motion Compensation System for Stereotactic Radiosurgery in a Realistic Clinical Environment with Healthy Volunteers.

Liu X, Sakaamini A, Gu W, Denis C et al.

PurposeStereotactic radiosurgery (SRS) is a nonsurgical method for treating brain abnormalities and small tumors. Traditional high-accuracy SRS requires a rigid metal head frame screwed into the skull…

TherapeuticPeer-ReviewedPubMedSupportive care in cancer · 2025

Effect of music therapy and relaxation visualization intervention on mask anxiety in head and neck cancer patients undergoing radiotherapy-a randomized controlled trial.

Joshi AM, Mehta SA, Tandiya P, Sonwani V et al.

PurposeHead and neck cancer (HNC) patients undergoing radiation therapy (RT) often experience mask anxiety due to the use of thermoplastic masks for immobilization. This study evaluated the effectiven…

TherapeuticQA & dosimetry📖 Free full textCited 1×Peer-ReviewedPubMedMedical physics · 2025

Effect of immobilization mask and beam energy on dose coverage to small joints in treating osteoarthritis with low-dose radiation therapy.

Ding GX, Homann KL, Shinohara ET.

PurposeOsteoarthritis (OA) is the most common form of arthritis, affecting over 32 million Americans. Low dose radiation therapy (LDRT) is being used to treat OA, including small joints. Treatment ene…

TherapeuticPeer-ReviewedPubMedRadiography (London, England · 2025

A comparative study of 6D skull motion assessment and positional satisfaction between two classical hair setup variations of female patients with brain lesions treated using cyberknife stereotactic radiosurgery.

Roy S, Suryavanshi K, Sridhar PS, Visariya B et al.

IntroductionThe CyberKnife® (CK) system is capable of treating localised brain lesions with the help of a 6D skull tracking system. Hair position plays a crucial role in the success of CK radiosurgery…

Therapeutic📖 Free full textCited 1×Peer-ReviewedPubMedAdvances in radiation oncology · 2025

Evaluating the Impact of Invasive Intubation on Treatment Accuracy in Head and Neck Cancer Patients Undergoing Image-Guided Radiation Therapy.

Kang CL, Huang YY, Wang JC, Li FJ et al.

PurposeTo assess how nasogastric and tracheostomy tubes affect the precision of image-guided radiation therapy (IGRT) in head and neck cancer (HNC) patients.Methods and materialsA retrospective analys…

Therapeutic📖 Free full textCited 4×Peer-ReviewedPubMedRadiation oncology (London, England) · 2025

Effectiveness of personalized open-face mask combined with styrofoam fixation in radiotherapy treatment of head and neck cancers: a prospective randomized controlled trial.

Yang F, Li J, Li B, Zhang L et al.

ObjectiveThe primary aim of this investigation is to assess the effectiveness of implementing an innovative immobilization approach, spec ically the utilization of personalized open-face masks in comb…

Therapeutic📖 Free full textPeer-ReviewedPubMedJournal of neurosurgery. Case lessons · 2025

Not one size fits all: a half-mask-based GKRS treatment for preservation of a scalp flap. Illustrative case.

Goulenko V, Madhugiri VS, Almeida ND, Podgorsak MB et al.

BackgroundImplementing the thermoplastic mask as a treatment option in Gamma Knife radiosurgery (GKRS) has madethe discussion of the relative benefits of frame- or mask-based fixation for treatment a …

QA & dosimetryTherapeutic📖 Free full textCited 2×Peer-ReviewedPubMedJournal of applied clinical medical physics · 2025

Assessing the rigidity of thermoplastic masks for head immobilization effectiveness in stereotactic radiosurgery.

Apale IP, Agnew A, Foley D.

This study compared three Brainlab thermoplastic masks-Cranial 4pi basic, stereotactic (Close Mask V2), and open-face-to see how well they limited head movement during Stereotactic Radiosurgery (SRS).…

QA & dosimetry📖 Free full textCited 2×Peer-ReviewedPubMedTechnology in cancer research & treatment · 2025

Dosimetric and Radiobiological Impact of Patient Setup Errors in Intensity-modulated Radiotherapy for Esophageal Cancer.

Cai JH, Peng X, Lu JY, Lu JY.

PurposeTo evaluate the impact of patient setup errors on the dosimetry and radiobiological models of intensity-modulated radiotherapy (IMRT) for esophageal cancer.Methods and materialsThis retrospecti…

QA & dosimetry📖 Free full textCited 3×Peer-ReviewedPubMedJournal of applied clinical medical physics · 2025

Efficacy of a thermoplastic mask and pneumatic abdominal compression device for immobilization in stereotactic ablative radiotherapy of spine metastases.

Walter YA, Speir DB, Burrell WE, Wang CJ et al.

Stereotactic ablative radiotherapy (SABR) has become a key technique in management of spine metastases. With improved control over treatment plan dosimetry, there is a greater need for accurate patien…

QA & dosimetry📖 Free full textCited 2×Peer-ReviewedPubMedJournal of applied clinical medical physics · 2025

Impact of belly board immobilization devices and body mass factor on setup displacement using daily cone-beam CT in rectal cancer radiotherapy.

Ruan J, Huang X, Wang T, Mai X et al.

ObjectiveThe objective of this study is to evaluate the impact of different belly board and daily changes in patient's body-mass factor (BMF) on setup displacement in radiotherapy for rectal cancer.Me…

Therapeutic📖 Free full textPeer-ReviewedPubMedTechnical innovations & patient support in radiation oncology · 2024

A prospective randomized study comparing two frameless immobilization systems for cranial stereotactic radiotherapy.

Callens D, Benazzouz C, Stessens L, Piot W et al.

IntroductionThe Dual Shell Encompass Fibreplast™ System (DS-Encompass) by CQ Medical™ is validated for frameless immobilization in stereotactic brain radiotherapy. An alternative mask model has been p…

Therapeutic📖 Free full textCited 1×Peer-ReviewedPubMedTechnology in cancer research & treatment · 2024

Patient Cranial Angle and Intrafractional Stability in CyberKnife Robotic Radiosurgery: A Retrospective Analysis.

Kang CL, Huang YY, Chen YR, Tsai SH et al.

Purpose: The aim of this study was to investigate whether variations in cranial angles and treatment accuracy during CyberKnife robotic radiosurgery necessitate adjustment of the margins of the planni…

Therapeutic📖 Free full textCited 2×Peer-ReviewedPubMedClinical and translational radiation oncology · 2023

A total inverse planning paradigm: Prospective clinical trial evaluating the performance of a novel MR-based 3D-printed head immobilization device.

Jablonska PA, Parent A, La Macchia N, Chan HHL et al.

Background and purposeBrain radiotherapy (cnsRT) requires reproducible positioning and immobilization, attained through redundant dedicated imaging studies and a bespoke moulding session to create a t…

Therapeutic📖 Free full textCited 2×Peer-ReviewedPubMedJournal of applied clinical medical physics · 2023

Mask dependency of the lacrimal gland dose under whole brain radiotherapy when the six-degrees of freedom couch is not available.

Yoon JW, Kim MY, Park S, Cheong KH et al.

BackgroundDry eye syndrome has been recently reported in patients who underwent whole brain radiotherapy (WBRT). WBRT based on a couch with three-degrees of freedom (3D) can occasionally be performed …

QA & dosimetry📖 Free full textCited 5×Peer-ReviewedPubMedTechnology in cancer research & treatment · 2021

Compare of Interfractional Setup Reproducibility Between Vacuum-Lock Bag and Thermoplastic Mask in Radiotherapy for Breast Cancer.

Song Y, Peng J, Chen Q, Luo H.

Background: This study aimed to analyze the difference of setup reproducibility between Vacuum-lock bag and Thermoplastic mask in the radiotherapy for breast cancer. Methods: A total of 100 invasive b…

QA & dosimetry📖 Free full textCited 25×Peer-ReviewedPubMedRadiation oncology (London, England) · 2019

Intrafractional 6D head movement increases with time of mask fixation during stereotactic intracranial RT-sessions.

Mangesius J, Seppi T, Weigel R, Arnold CR et al.

BackgroundThe present study investigates the intrafractional accuracy of a frameless thermoplastic mask used for head immobilization during stereotactic radiotherapy. Non-invasive masks cannot complet…

QA & dosimetryCited 45×Peer-ReviewedPubMedJournal of neurosurgery · 2018

Assessment of motion error for frame-based and noninvasive mask-based fixation using the Leksell Gamma Knife Icon radiosurgery system.

Carminucci A, Nie K, Weiner J, Hargreaves E et al.

OBJECTIVEThe Leksell Gamma Knife Icon (GK Icon) radiosurgery system can utilize cone-beam computed tomography (CBCT) to evaluate motion error. This study compares the accuracy of frame-based and frame…

Therapeutic📖 Free full textCited 49×Peer-ReviewedPubMedJournal of medical radiation sciences · 2018

Exploring the prevalence and experience of mask anxiety for the person with head and neck cancer undergoing radiotherapy.

Nixon JL, Cartmill B, Turner J, Pigott AE et al.

IntroductionWhile use of a thermoplastic mask during radiotherapy (RT) treatment for head and neck cancer (HNC) is an essential component of safe patient care, there is little understanding of the ext…

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