Patient Immobilization · Literature Radar
Soft-tissue fiducial markers for IGRT — prostate, liver, lung, pancreas. Anchoring vs migration evidence. Curated daily from Europe PMC (PubMed + PMC + preprints) and OpenAlex — free-full-text link on each open-access paper.
Iizumi T, Ishikawa H, Sekino Y, Murakami M et al.
The purpose of the present study is to confirm the efficacy and feasibility of moderately hypofractionated proton beam therapy (PBT) at a total dose of 63 Gy relative biological effectiveness (RBE) in…
Kan F, Jin F, Mylonas A, Zwan B et al.
During radiation therapy, liver tumor motion can reduce dose delivery accuracy and increase irradiation of adjacent healthy tissues. Because liver tumors are difficult to visualize directly on kilovol…
Takeuchi K, Ishikawa T, Yamao K, Mizutani Y et al.
High geometric precision is essential in proton beam therapy (PBT) for pancreatic cancer. This study evaluated inter-fraction positional accuracy during image-guided PBT using radiopaque surrogates an…
Watanabe Y, Maeyama T, Mizukami S, Shimo T et al.
PurposeThis study aims to utilise an iodine-doped magnetic resonance (MR)-based polymer gel dosimeter to achieve three-dimensional (3D) dose-distribution measurement combined with accurate target visu…
Coskun M, Petersson JS, Wetterstedt SA, Brynolfsson P et al.
Magnetic resonance imaging (MRI) offers superior soft-tissue contrast and MRI-only radiotherapy (RT) eliminates uncertainties associated with computed tomography (CT)-to-MRI image registration. An MRI…
Moseley TW, Adrada BE, Arribas EM, Urban MW et al.
Breast biopsy markers have evolved from simple metallic markers to sophisticated multimaterial devices that serve critical purposes throughout the breast cancer care continuum. This evolution began at…
Ueno M, Yamanouchi Y, Hanazawa H, Takabatake H et al.
Background/Objectives : Stereotactic body radiotherapy (SBRT) is increasingly used for hepatocellular carcinoma (HCC) that is unsuitable for surgery, radiofrequency ablation (RFA), or transplantation.…
Kaczynska A, Jin F, Stewart M, Kipritidis J et al.
Objective.Real-time six-degree-of-freedom (6DoF) tumour motion monitoring is important for accurate stereotactic body radiotherapy (SBRT) of thoracic and abdominal cancer sites, yet existing approache…
Wei J, Chao M, Narang A, Mao W.
Breath-hold (BH) techniques reduce respiratory motion and planning margins in thoracic and abdominal radiotherapy, but residual motion during BH can still compromise targeting accuracy. Direct tumor t…
Hayashi A, Takahashi Y, Sanuki N, Yamashita Y et al.
BackgroundPrecise target definition in prostate radiotherapy requires accurate computed tomography (CT)-magnetic resonance imaging (MRI) image registration using gold fiducial markers (GFMs). While mu…
Ebinuma Y, Inoue T, Shirata R, Takatsu J et al.
ObjectivesTo compare the dosimetry and robustness of two Radixact Synchrony lung stereotactic body radiotherapy (SBRT) tracking strategies: tumour-based lung tracking with respiratory modelling (LwR) …
Kang T, Armstrong S, Chander S, de Leon J et al.
PurposeProstate stereotactic ablative body radiotherapy (SABR) is now a standard-of-care radiation therapy option for prostate cancer based on high-level clinical trial evidence. As part of the Austra…
Quintero P, Yu V, Wu C, Smith L et al.
Introduction.This study aims to generate synthetic-magnetic resonance imaging (synMRI) for abdominal patients undergoing radiotherapy using deep inspiration breath hold (DIBH) on a conventional Linac.…
Shoji J, Ohta K, Suzuki K, Horibe A et al.
Purpose This study aimed to evaluate the feasibility and safety of percutaneous fiducial marker placement using a 25G needle compared with transarterial placement before proton therapy for pancreatic …
Iwai T, Yoneyama M, Kishi N, Adachi T et al.
Background and Purpose: For thoracic and upper abdominal tumours, respiratory motion management is essential; dynamic tumour-tracking radiotherapy (DTT-RT) is one such approach, but it typically requi…
Nankali S, Worm ES, Thomsen JB, Stick LB et al.
PurposePencil beam scanning proton therapy of hepatocellular carcinoma (HCC) may reduce the risk of radiation-induced liver disease compared to photon radiotherapy, but tumor motion and anatomical cha…
Retif P, Sidikou AD, Saleh M, Letellier R et al.
PurposeTo compare the accumulated kerma-in-air associated with intrafraction fiducial-based prostate localization in stereotactic body radiotherapy (SBRT) across three clinical platforms: Varian TrueB…
Cao X, Reed MS, Culberson WS, Pogue BW.
Accurate beam targeting is critical in radiation therapy, particularly for stereotactic treatments of mobile organs where fiducial markers are routinely used for image guidance. However, current appro…
Mihashi N, Hinoto R, Kawase T, Tsukamoto N.
Gold fiducial markers (GMs) are widely used in prostate radiotherapy; however, their magnetic susceptibility can reduce visibility on T2-weighted (T2w) MRI and may compromise CT-MRI registration. Usin…
Terashima K, Gentsu T, Takahashi D, Matsuo Y et al.
This study evaluated the safety, feasibility and efficacy of endovascular pulmonary arterial fiducial marker (EVFM) placement for image-guided particle therapy using proton or carbon-ion beams in pati…
Zhang X, Andriotty M, Yue NJ, Nie K et al.
BackgroundIn radiotherapy, it is not uncommon to treat patients with metallic implants. Those implants often cause significant amount of artifacts on the simulation CT images, and the intrinsic Hounsf…
Schaly B, Mendez LC, Khawaja M, Black A et al.
IntroductionThe multi-institutional HOPE trial (NCT04197141) compared conventional (25 fractions over 5 weeks) to ultra-hypofractionated (5 fractions over 1.5 weeks) whole pelvis radiotherapy for unfa…
Hayhurst W, Uribe-Lewis S, Uribe J, Mikropoulos C et al.
Introduction Long-term follow-up after low-dose rate brachytherapy and ultra-fractionated radiotherapy for localised prostate cancer has demonstrated impressive survival statistics with low toxicity p…
Müssgens C, Roth B, Arnold N, Schneidewind L et al.
BACKGROUND: Fiducial markers are commonly used to guide precise radiotherapy in prostate cancer patients. While intraprostatic migration has been described, transcutaneous displacement during biopsy i…
Serpa M, Wiehle R, Rothe T, Küchler S et al.
Background and purpose Intrafraction motion degrades the efficacy of radiation therapy. We reported on the implementation of focal dose-escalated stereotactic body radiation therapy (HypoFocal-SBRT) f…
Abellan C, Mouraux S, Janett S, von Garnier C et al.
BackgroundPulmonary fiducial markers (FMs) allow real-time tracking for stereotactic body radiotherapy (SBRT) by CyberKnife, which is an alternative to surgery in early-stage inoperable non-small-cell…
Liu J, Bamberger C, Iqbal N, Reynolds K et al.
PurposeIntegrating multiple radiotherapy modalities, including photon and proton therapy, within a single clinical facility requires universal fiducial markers that perform reliably across all imaging…
Miyabe Y, Yamanaka H, Seki H, Iwata H et al.
Respiratory motion of tumors and surrounding organs at risk (OARs) is a critical factor affecting dose distribution and treatment accuracy in radiotherapy. The CyberKnife Synchrony respiratory trackin…
Zapatero A, Castro P, Martin de Vidales C, Roch M et al.
ObjectivesTo evaluate how the implementation of intensity-modulated/image-guided RT (IMRT/IGRT) with intraprostatic seeds can impact the risk of late gastrointestinal (LGI) and genitourinary (LGU) tox…
Nagata J, Kusano Y, Komori M, Takayama Y et al.
Background Carbon-ion radiotherapy (CIRT) delivers highly conformal tumor doses while sparing surrounding organs-at-risk (OAR). However, density variations along the beam path and interfractional targ…
Worth M, Brancato DC, Lo J, Kole TP.
BackgroundPlanning target volume (PTV) margin reduction has been demonstrated to result in decreased acute genitourinary and gastrointestinal toxicity in patients treated with definitive stereotactic …
Chrystall D, Stewart M, Jin F, Sengupta C et al.
BackgroundReal-time image-guided radiotherapy (IGRT) is critical for accurate dose delivery during stereotactic body radiotherapy (SBRT). Beam's eye view (BEV) imaging offers the unique advantage of r…
Takemasa K, Kato T, Sasaki S, Narita Y et al.
Image-guided passive scattering proton therapy (PSPT) has been widely adopted in Japan and worldwide, with substantial long-term clinical data supporting its efficacy in treating prostate cancer. Howe…
Coskun M, Brynolfsson P, Gustafsson CJ, Gunnlaugsson A et al.
Background Fiducial markers in image-guided prostate cancer radiotherapy reduce geometric uncertainty during daily patient setup and enable assessment of target position changes. Diffusion-weighted ma…
Stas D, Vandamme T, Roeyen G, Reynders D et al.
Background Patients with pancreatic ductal adenocarcinoma face a poor prognosis, with radical resection being the only potential cure. Because symptoms typically appear late, many patients are diagnos…
Kato D, Abo D, Morita R, Katoh N et al.
PurposeTo assess and compare the feasibility and safety of transarterial and percutaneous fiducial marker placements for gated radiotherapy using real-time tumor-tracking (RTRT) in patients with pancr…
Titone F, Moretti E, Poli A, Guernieri M et al.
Purpose: To present the findings of our preliminary experience using daily image-guided radiotherapy (IGRT) supported by implanted fiducial markers (FMs) in the radiotherapy of the vaginal cuff, in a …
Tan HQ, Koh CWY, Lew KS, Yeap PL et al.
Introduction Real-time gated proton therapy (RGPT) is a motion management technique unique to the Hitachi particle therapy system. It uses pulsed fluoroscopy to track an implanted fiducial marker. The…
Cazacu IM, Singh BS, Martin-Paulpeter RM, Beddar S et al.
Accurate delivery of stereotactic body radiotherapy (SBRT) to pancreatic tumors relies on successful EUS-guided placement of fiducial markers. The aim of this study is to report the technical feasibil…
Breazeale A, Rahmani R, Gallagher K, Nabavizadeh N.
IntroductionFor liver stereotactic body radiation therapy (SBRT), the placement of fiducial markers or retained ethiodized oil by transarterial chemoembolisation (TACE) provides a landmark for consist…
Kita N, Tomita N, Takaoka T, Okazaki D et al.
Background and purpose The present study attempted to identify risk factors for symptomatic radiation pneumonitis (RP) after stereotactic body radiotherapy (SBRT) in patients with early-stage non-smal…
Cloitre M, Valerio M, Mampuya A, Rakauskas A et al.
Objectives We conducted a phase I/II prospective trial to determine whether stereotactic dose escalation to the dominant intra-prostatic nodule (DIN) up to 50 Gy incorporating a rectal balloon spacer …
Tascón-Vidarte JD, Stick LB, Josipovic M, Risum S et al.
We investigate the accuracy of intensity-based deformable image registration (DIR) for tumor localization in liver stereotactic body radiotherapy (SBRT). We included 4DCT scans to capture the breathin…
Miszczyk M, Rembak-Szynkiewicz J, Magrowski Ł, Stawiski K et al.
Prostate Imaging-Reporting and Data System (PI-RADS) has been widely implemented as a diagnostic tool for significant prostate cancer (PCa); less is known about its prognostic value, especially in the…
Iizumi T, Ishikawa H, Sekino Y, Tanaka K et al.
Introduction To confirm the feasibility of hypofractionated proton beam therapy (PBT), we compared the acute adverse event rates and International Prostate Symptom Score (IPSS) in prostate cancer pati…
Tsubouchi T, Hamatani N, Takashina M, Wakisaka Y et al.
Purpose Carbon ion radiotherapy for prostate cancer was performed using two fine needle Gold Anchor (GA) markers for patient position verification in Osaka Heavy Ion Medical Accelerator in Kansai (Osa…
Iwata H, Ogino H, Hattori Y, Nakajima K et al.
This study retrospectively investigated the efficacy and safety of image-guided proton therapy (IGPT) for elderly (≥80 years old) hepatocellular carcinoma (HCC) patients. Proton therapy was performed …
Kok END, Eppenga R, Kuhlmann KFD, Groen HC et al.
In the past decades, image-guided surgery has evolved rapidly. In procedures with a relatively fixed target area, like neurosurgery and orthopedics, this has led to improved patient outcomes. In cance…
Böckelmann F, Putz F, Kallis K, Lettmaier S et al.
Purpose To investigate the dosimetric influence of daily interfractional (inter) setup errors and intrafractional (intra) target motion on the planning target volume (PTV) and the possibility of an of…
Korpics MC, Rokni M, Degnan M, Aydogan B et al.
Background Fiducial markers are frequently used before treatment for image-guided patient setup in radiation therapy (RT), but can also be used during treatment for image-guided intrafraction motion d…
Osman SOS, Russell E, King RB, Crowther K et al.
Background In this study, a novel pelvic phantom was developed and used to assess the visibility and presence of artefacts from different types of commercial fiducial markers (FMs) on multi-modality i…
Rigter LS, Rijkmans EC, Inderson A, van den Ende RPJ et al.
Background and study aims To facilitate image guidance during radiotherapy of rectal cancer, we investigated the feasibility of fiducial marker placement. This study aimed to evaluate technical succes…
Scher N, Bollet M, Bouilhol G, Tannouri R et al.
Purpose The purpose of this study was to assess the feasibility, efficacy and toxicity of fiducial marker implantation and tracking in CyberKnife® stereotactic radiation therapy (SBRT) applied to extr…
Alayed Y, Cheung P, Chu W, Chung H et al.
PurposeUltrahypofractionation is appealing for prostate cancer (PCa) due to low α/β, and increasing the dose per fraction could improve the therapeutic index. Here we report the outcomes of a phase II…
van den Ende RPJ, Rigter LS, Kerkhof EM, van Persijn van Meerten EL et al.
Background and purpose A GTV boost is suggested to result in higher complete response rates in rectal cancer patients, which is attractive for organ preservation. Fiducials may offer GTV position veri…
Nakajima K, Iwata H, Ogino H, Hattori Y et al.
Background Two prospective phase II trials were designed to assess the efficacy and safety of image-guided proton therapy (IGPT) for either medically inoperable or operable stage I non-small cell lung…
Baumann R, Chan MKH, Pyschny F, Stera S et al.
Introduction We retrospectively evaluated the efficacy and toxicity of gross tumor volume (GTV) mean dose optimized stereotactic body radiation therapy (SBRT) for primary and secondary lung tumors wit…
Tanaka O, Nishigaki Y, Hayashi H, Iida T et al.
Radiotherapy for liver malignancy is increasing due to advances in radiotherapy technique. Visualization of the tumor as well as fiducial markers is essential. To see if improved visibility exists on …
Versteijne E, Gurney-Champion OJ, van der Horst A, Lens E et al.
Background The delineation of pancreatic tumors on CT is challenging. In this study, we quantified the interobserver variation for pancreatic tumor delineation on 3DCT as well as on 4DCT. Methods Eigh…
Shimohigashi Y, Toya R, Saito T, Ikeda O et al.
BackgroundFor stereotactic body radiation therapy (SBRT) of liver tumors, tumor motion induced by respiration must be taken into account in planning and treatment. We evaluated whether liver tumor mot…
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